Experimental models in physiology

27 June 2018 - 29 June 2018

University of Exeter, Exeter, United Kingdom


Wednesday, 27 June

Mighty mouse and the might of other models

9.00 Plenary lecture
Philip Ingham, University of Exeter, UK

10.00 Refreshments

Why is the mouse not so mighty?

10.30 Mouse – No
David Wyllie, University of Edinburgh, UK

11.00 Mouse – Yes

11.30 Debate

12.00 Lunch 

12.45 Oral communications

14.15 Refreshments

Complementary models

14.30 Anthony Graham, King’s College London, UK

15.00 Tom Smulders, Newcastle University, UK

15.15 TBC

15.30 Tim Chico, University of Sheffield, UK

16.00 Poster session

17.30 Keynote lecture
Stuart Egginton, University of Leeds, UK 

18.30 End of day one


Thursday, 28 June

Pathophysiological models: Cells to complex systems

9.00 Plenary lecture: A systems approach to muscle adaptation
Claire Stewart, Liverpool John Moores University, UK

10.00 Refreshments

Insights from animal models of human disease 

10.30 Kevin Maloy, University of Oxford, UK

11.00 Robert Menzies, University of Edinburgh, UK 

11.15 Chrissy Hammond, University of Bristol, UK

11.30 Alan Stitt, Queen’s University Belfast, UK 

12.00 Lunch

Workshop: My local AWERB - what's in it for me?
Penny Hawkins and Maggy Jennings, RSPCA, UK

12.45 Oral communications

14.15 Refreshments

Towards human models

14.30 Rachel Watson, University of Manchester, UK

15.00 Amanda Sferruzzi-Perri, University of Cambridge, UK 

15.15 Emily Mavin, Newcastle University, UK 

15.30 Humanized mice to investigate neurodegenerative diseases
Edgar Kramer, University of Plymouth, UK

16.00 Poster session 

17.30 Keynote lecture 
Godfrey Smith, University of Glasgow, UK

19.00 Conference dinner


Friday, 29 June

Future directions: Opportunities and challenges

9.00 Plenary lecture
Jamie Davies, University of Edinburgh, UK 

10.00 Refreshments

10.15 Replicating human disease in rodents: the good and the bad of CRISPR/Cas9 genome editing
Guillaume Pavlovich, Institut Clinique de la Souris, France

10.45 A quantitative systems pharmacology approach to understanding candidate drug mechanisms of action
Emily Roasha, University of Reading, UK

11.15 TBC

11.45 Computational modelling
Jeroen Jeneson, University of Groningen, Netherlands 

12.15 Lunch and networking