Proceedings of The Physiological Society

University of Bristol (2001) J Physiol 536P, S104

Communications

Developmental expression of androgen receptor and 3β-hydroxysteroid dehydrogenase (3β-HSD) in the urogenital tract of the grey short-tailed Brazilian opossum (Monodelphis domestica)

A.J. Russell, D.P. Gilmore, S. Mackay, S.L. Ullmann and A.P. Payne

Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK


In eutherian mammals, sex differentiation is initiated by expression of the testis-determining gene on the Y chromosome. Subsequent phenotypic development of the reproductive tract and genitalia depends on the production of hormones by the differentiated testis. Thus masculinisation of the phenotype is controlled by androgens and anti-M

Where applicable, experiments conform with Society ethical requirements