Proceedings Abstracts of The Physiological Society

Smooth Muscle

Deletion of the ion channel TRPV4 increases detrusor contractility in the mouse

A. C. Ramos-Filho2, F. Johnson1, E. Antunes2, A. Grant1

Proc Physiol Soc 30 (2013)

Decreased TRPV4 activity in female mouse bladder enhances muscarinic contractions

F. Johnson1, A. C. Ramos-Filho2, A. Shah1, E. Antunes2, A. Grant1

Proc Physiol Soc 30 (2013)

Endothelial SHIP2 confers age-dependent contrasting affects on whole body glucose homeostasis and vascular function

M. Gage1, S. Wheatcroft1, A. Abbas1, H. Imrie1, H. Viswambharan1, S. Galloway1, P. Sukumar1, R. Cubbon1, J. Smith1, S. Schurmans2, M. Jacoby2, E. Dubois2, M. Kearney1

Proc 37th IUPS (2013)

The impact of advanced maternal age on the initiation and progress of parturition in a pregnant mouse model

R. Patel1

Proc 37th IUPS (2013)

Phosphodiesterase-5 activity exerts a coronary vasoconstrictor influence in awake swine that is partly mediated via an increase in endothelin production

Z. Zhou1, V. J. de Beer1, S. B. Bender2, H. Laughlin2, D. Merkus1, D. J. Duncker1

Proc 37th IUPS (2013)

A toxicity profile of the aqueous calyx extract of Hibiscus sabdariffa in Sprague Dawley rats

F. B. Mojiminiyi1

Proc 37th IUPS (2013)

Endothelial relaxation mechanisms dysfunction are reversed by atorvastatin or metformin in animals with estrogen deficiency state

I. F. Caliman1, P. W. Oliveira1, A. Z. Lamas1, S. G. Figueiredo1, P. L. Dalpiaz1, G. J. Sousa1, N. S. Bissoli1

Proc 37th IUPS (2013)

Kv7 channels are major determinants of basal coronary flow and active response to ischemia

S. Khanamiri1, E. Soltysinska1, T. A. Jepps2, B. H. Bentzen1, P. S. Chadha2, N. Schmitt1, I. A. Greenwood2, S. Olesen1

Proc 37th IUPS (2013)

Cardioprotection from cold stress and subsequent fatty diet is mediated by Epac-1 in the isolated mouse heart

F. Edland1

Proc 37th IUPS (2013)

Flow-mediated outward remodeling and NO-dependent dilation of resistance arteries are both determined by sex and age with a key role of timing in estradiol replacement therapy

K. Tarhouni1, A. Guihot1, L. Grimaud1, B. Toutain1, L. Loufrani1, F. Lenfant2, J. Arnal2, D. Henrion1

Proc 37th IUPS (2013)

The effect of l-arginine on microvascular reactivity in normotensive subjects with family history of hypertension

Z. Melik1, P. Zaletel1, T. Virtic1, K. Cankar1

Proc 37th IUPS (2013)

Improvement of blood-retinal barrier breakdown in type 2 diabetic rats by alpha-mangostin

C. Areebambud1, C. Mekseepralard2, A. Jariyapongskul1

Proc 37th IUPS (2013)

Neuropilin-1 regulates endothelial focal adhesion turnover via p130Cas phosphorylation.

I. Evans1, W. Pickworth1, G. Schey1, P. Frankel1, I. C. Zachary1

Proc 37th IUPS (2013)

The role of Na+/H+ exchanger-1 during ischemia-induced cerebrovascular dysfunction

Y. Jung1

Proc 37th IUPS (2013)

Assessment of arterial distensibility in patients with sarcoidosis

H. Balci1, S. Sipahi Demirkok2, M. Yildiz3, G. Metin3, M. Hacibekiroglu1, G. Simsek3

Proc 37th IUPS (2013)

Increased permeability of pulmonary arterioles after cardiopulmonary bypass.

T. Beleznai1, L. Walker2, R. Ascione2, K. A. Dora1

Proc 37th IUPS (2013)

Peripheral circulatory changes during Valsalva maneuver using DC component of Photoplethysmographic signal

D. S. Chandran1, A. J. Kattoor1, A. K. Jaryal1, K. K. Deepak1

Proc 37th IUPS (2013)

Aliskiren associate with L-Arginine improves vascular reactivity of renovascular hypertension rats

C. Santuzzi1, R. V. Tiraddentes1, V. Mengal1, H. Mauad1, P. Matos1, S. A. Gouvea1, M. H. Cunha1, G. R. Abreu1

Proc 37th IUPS (2013)

Pharmacological analysis of sympathetically-mediated constriction in wild type and +

C. Stevenson1, C. Daly1, E. McLachlan2, I. McGrath1

Proc 37th IUPS (2013)

Mathematical modelling of capillary O2 supply capacity in cardiac and skeletal muscle

A. A. Al-Shammari1, E. A. Gaffney1, S. Egginton2,3

Proc 37th IUPS (2013)

The effects of Insulin-like Growth Factor Binding Protein-1 on endothelial repair in the insulin resistant setting

A. Aziz1, N. Yuldasheva1, J. Smith1, N. Haywood1, P. Cordell1, R. Cubbon1, K. E. Porter1, M. T. Kearney1, S. B. Wheatcroft1

Proc 37th IUPS (2013)

Tissue- and agonist-specific isolated murine arterial responses to ageing.

C. Nicholson1, M. Sweeney1, S. C. Robson1, M. J. Taggart1

Proc 37th IUPS (2013)

Curcumin could ameliorate diabetic vascular inflammation by decreasing ROS overproduction, leukocyte-endothelium interaction, and NOX2 expression

N. Wongeakin1, P. Bhattarakosol2, S. Patumraj1

Proc 37th IUPS (2013)

Apocynin prevents vascular effects caused by chronic exposition to low concentrations of mercury

J. T. Dini1, D. Rizzetti1, F. Maciel Peçanha1, D. Valentim Vassalo1, G. Wiggers1

Proc 37th IUPS (2013)

Sulforaphane pre-treatment reduces Nrf2 content in core and peri-infarct brain regions in rats subjected to ischaemia-reperfusion injury

S. Srivastava1, A. Alfieri1, R. C. Siow1, P. A. Fraser1, G. E. Mann1

Proc 37th IUPS (2013)

Interaction of Sequestosome1/p62 with voltage-activated potassium channels in arterial smooth muscle cells in injury-induced arterial remodeling

T. Ishii1, E. Warabi1, R. C. Siow2, G. E. Mann2

Proc 37th IUPS (2013)

Inhibitory Effects of Sprouty4 on proliferation and migration of vascular smooth muscle cells involving in suppression of MAPK and Akt double signal pathways

H. Li1,2, X. Yang2, R. Liaw2, Y. Shi3, S. Ma4, B. Friesel2

Proc 37th IUPS (2013)

TRPV1 and autocrine serotonin signalling elicit Ca2+ release from the acidic organelles of ADP-stimulated human platelets.

S. Sage1, A. Harper2

Proc 37th IUPS (2013)

Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca2+-sensitive K+ channels in rat mesenteric artery

O. Roberts1, T. Kamishima2, R. Barrett-Jolley3, J. M. Quayle2, C. Dart1

Proc 37th IUPS (2013)

Role of Nitric Oxide in the control of the SR Ca2+ release in myocytes of arteriolar networks in situ

L. Borysova1, S. Wray1, D. A. Eisner2, T. Burdyga1

Proc 37th IUPS (2013)

Asthmatic cytokines IL-13 and TGF+

Y. Shaifta1, D. B. Wright1, V. Snetkov1, J. P. Ward1

Proc 37th IUPS (2013)

Mechanisms regulating localized and global calcium responses in vascular cells

N. Tsoukias1, A. Kapela1, J. Parikh1

Proc 37th IUPS (2013)

Is platelet mediated leukocyte recruitment a potential therapeutic target in atherosclerosis?

M. Harrison1, G. B. Nash1, S. P. Watson1, E. Rainger1

Proc 37th IUPS (2013)

The role of Na+/Ca2+ exchange and ER Ca2+ buffering in the regulation of oxytocin-induced [Ca2+]i oscillations.

B. Hamilton1, Y. Timofeeva2, A. Shmygol3

Proc 37th IUPS (2013)

Restoring Akt1 activity in endothelial progenitors from insulin resistant humans rescues vascular reparative capacity

R. Cubbon1, N. Yuldasheva1, H. Viswambharan1, B. Mercer1, V. Baliga1, S. Stephen1, J. Askham1, P. Sukumar1, A. Skromna1, R. Mughal1, H. Imrie1, M. Gage1, M. Rakobowchuk1, J. Li1, K. Porter1, S. Ponnambalam1, S. Wheatcroft1, D. Beech1, M. Kearney1

Proc 37th IUPS (2013)

The effect of IL-6 -174 G/C polymorphism on adiponectin and IL-6 Levels in peripheral vascular disease

N. Salmayenli2,3, E. Özkök1,2, Y. Basar3,2

Proc 37th IUPS (2013)

Applications of pulse-driven magnetoimpedance sensors to biological magnetic fields

S. Nakayama1, S. Atsuta3, M. Kondo1, T. Uchiyama2

Proc 37th IUPS (2013)

Renal transplantation improves baroreflex sensitivity and arterial stiffness in end stage renal disease patients

M. Kaur1, D. S. Chandran1, C. Lal2, D. Bhowmik2, A. K. Jaryal1, K. K. Deepak1, S. K. Agarwal2

Proc 37th IUPS (2013)

Sympathetic Vascular reactivity to cold pressor test in Parkinson's disease and Parkinsonian variant of Multiple System Atrophy with orthostatic hypotension

S. Roy1, A. K. Jaryal1, A. K. Srivastava2, K. K. Deepak1

Proc 37th IUPS (2013)

Pericytes derived from the human foetal kidney are progenitors for renin-producing cells

A. Stefanska1, J. Mullins1, B. Péault1,2

Proc 37th IUPS (2013)

Intravital investigations of lymphocyte and platelet recruitment to murine liver following ischemia-reperfusion injury

J. Robinson1, D. H. Adams1, N. Kalia1

Proc 37th IUPS (2013)

The effect of L-arginine on the function of the microvascular endothelium in healthy trained and sedentary subjects

K. Cankar1, T. Virtic1, P. Zaletel1, Z. Melik1

Proc 37th IUPS (2013)

Molecular and functional changes of Cav1.2 channels in vascular smooth muscles after hypoxia

P. Liao1

Proc 37th IUPS (2013)

Bilobalide enhances coronary artery endothelial potassium currents

W. B. Watanapa1, T. Wongsatan1, K. Ruamyod1

Proc 37th IUPS (2013)

Bronchoconstrictor signal transduction involves protein kinase C-mediated phosphorylation of Kv7.5 potassium channels in human airway smooth muscle cells

J. M. Haick1, L. I. Brueggemann1, J. R. Prochot1, D. S. Randhawa1, C. Wigfield1, K. L. Byron1

Proc 37th IUPS (2013)

Heteromultimerization with TRPC1 affects TRPC5 channel function by regulating its plasma membrane residence and cholesterol-triggered retraction.

S. Tumova1,2, B. Hou1,2, M. S. Amer1,3, L. McKeown1,2, N. K. Moss1,2, Y. M. Bahnasi1,4, J. Li1,2, K. E. Porter2,3, A. Sivaprasadarao1,2, D. J. Beech1,2

Proc 37th IUPS (2013)

Overload of cholesterol inhibits L-type Ca2+ channel current and augments its voltage-dependent inactivation in A7r5 cells

R. Ochi1, S. Chettimada1, S. A. Gupte1

Proc 37th IUPS (2013)

PDGF maintains stored calcium through a non-clustering Orai1 mechanism but evokes clustering if the ER is stressed by store depletion

L. McKeown1,2, N. K. Moss1,2, P. Turner1,3, J. Li1,2, N. Heath1, D. Burke3, O. David3, M. S. Gilthorpe4, P. E. Karen1,2, D. J. Beech1,2

Proc 37th IUPS (2013)

Kv1.3 channel modulates human vascular smooth muscle cells proliferation acting on ERK1/2 signaling pathway.

T. Perez-Garcia1,2, P. Cidad1,2, E. Miguel-Velado1,2, C. Ruiz-McDavitt1,2, E. Alonso1,2, J. Lopez3, M. Fernández3, Y. Marroquín4, J. R. López-López1,2

Proc 37th IUPS (2013)

Study on mRNA and protein expression levels of small conductance calcium-activated potassium channel in human mesenteric artery from patients with hypertension

L. Mao1, T. Li1, H. Lan1, W. Huang1, R. Zhou1, C. Li1, P. Li1, Y. Yang1, X. Zeng1

Proc 37th IUPS (2013)