Proceedings Abstracts of The Physiological Society

Smooth Muscle

Flicker-assisted localisation microscopy reveals altered mitochondrial architecture in vascular smooth muscle in hypertension

S. Chalmers1, C. Saunter2, J. M. Girkin2, J. G. McCarron1

Proc Physiol Soc 31 (2014)

Evaluation of small molecule inhibitors of nuclear factor kappa B (NF+

L. R. Gurney1, J. Taggart1, S. Robson1, M. Taggart1

Proc Physiol Soc 31 (2014)

Further investigation into the role of Kv7 channels in +

K. S. Jahan1, J. B. Stott1, I. A. Greenwood1

Proc Physiol Soc 31 (2014)

Investigation of Kv7 (KCNQ) modulators on contractility of normal and overactive rat bladder

L. Baysting1, K. D. McCloskey1

Proc Physiol Soc 31 (2014)

Bone Morphogenetic Protein 4 (BMP4) Inhibits Platelet-Derived Growth Factor (PDGF)-Induced Collagen Synthesis in Pulmonary Artery Smooth Muscle Cells (PASMCs)

W. Han1, Y. Su1

Proc Physiol Soc 31 (2014)

Contractile desensitisation to UTP is enhanced in spontaneously-hypertensive rats only after hypertension is established

C. A. Nash2, R. Jackson1, R. Challiss2, J. M. Willets3, R. D. Rainbow1

Proc Physiol Soc 31 (2014)

Potassium channels contribute to vasorelaxant activities induced by Tridax procumbens aqueous leave extract in rat mesenteric artery

H. M. Salahdeen2,1, A. A. Alada1,2, B. A. Murtala1,2, A. O. Adebari2,1

Proc Physiol Soc 31 (2014)

Human mesenchimal stem cells transplant failed to restore vasodilator potential in vascular tissues from diabetic rats but succeeded in spontaneously hypertensive rats

A. I. Soloviev1, I. Ivanova2, T. Novokhatska3, K. Klymenko4

Proc Physiol Soc 31 (2014)

Altered expression of phosphoprotein enriched in astrocytes-15 in murine and human models of neointima hyperplasia

F. H. Greig1, S. Kennedy2, G. Gibson3, G. F. Nixon1

Proc Physiol Soc 31 (2014)

The role of Ca2+-activated Cl- channels in vascular smooth muscle cells

V. S. Dam1, C. Aalkjaer1, V. V. Matchkov1

Proc Physiol Soc 31 (2014)

Analysis Of Calmodulin Dependent Kinase II (CaMKII)-delta and -gamma subunit expression between three different human smooth muscle tissues

J. Lartey1, J. Taggart1, S. C. Robson1, M. J. Taggart1

Proc Physiol Soc 31 (2014)

Bioinformatic and experimental validation of 3' exon alternative splicing of Myosin Phosphatase Targeting (MYPT) subunits in human muscles

J. Lartey1, K. North1, J. Taggart1, S. C. Robson1, M. Taggart1

Proc Physiol Soc 31 (2014)

Direct visualisation of smooth muscle cell phenotypic plasticity and migration by long-term imaging

M. E. Sandison1, S. Chalmers1, J. Dempster1, J. G. McCarron1

Proc Physiol Soc 31 (2014)

Inhibition of human vascular smooth muscle cell migration occurs via exchange protein activated by cAMP (Epac)

J. S. McKean1, S. J. Tucker1, G. Gibson2, D. A. Shewan1, G. F. Nixon1

Proc Physiol Soc 31 (2014)

The effects of heating from 37-50oC on bladder spontaneous contractions

D. G. Kitney1, B. Vahabi2, R. I. Jabr1, C. H. Fry1

Proc Physiol Soc 31 (2014)

Resolvins do not relax isolated rat thoracic aorta

M. Jannaway1, A. P. Sampson1, J. A. Warner1, C. Torrens2

Proc Physiol Soc 31 (2014)

Functional role of CFTR in rat mesenteric artery

H. T. Pritchard1, N. Lee1, G. Carr1, A. P. Albert1, I. A. Greenwood1

Proc Physiol Soc 31 (2014)

Deletion of the ion channel TRPV4 increases detrusor contractility in the mouse

A. C. Ramos-Filho2, F. Johnson1, E. Antunes2, A. Grant1

Proc Physiol Soc 30 (2013)

Decreased TRPV4 activity in female mouse bladder enhances muscarinic contractions

F. Johnson1, A. C. Ramos-Filho2, A. Shah1, E. Antunes2, A. Grant1

Proc Physiol Soc 30 (2013)

Endothelial SHIP2 confers age-dependent contrasting affects on whole body glucose homeostasis and vascular function

M. Gage1, S. Wheatcroft1, A. Abbas1, H. Imrie1, H. Viswambharan1, S. Galloway1, P. Sukumar1, R. Cubbon1, J. Smith1, S. Schurmans2, M. Jacoby2, E. Dubois2, M. Kearney1

Proc 37th IUPS (2013)

The impact of advanced maternal age on the initiation and progress of parturition in a pregnant mouse model

R. Patel1

Proc 37th IUPS (2013)

Phosphodiesterase-5 activity exerts a coronary vasoconstrictor influence in awake swine that is partly mediated via an increase in endothelin production

Z. Zhou1, V. J. de Beer1, S. B. Bender2, H. Laughlin2, D. Merkus1, D. J. Duncker1

Proc 37th IUPS (2013)

A toxicity profile of the aqueous calyx extract of Hibiscus sabdariffa in Sprague Dawley rats

F. B. Mojiminiyi1

Proc 37th IUPS (2013)

Endothelial relaxation mechanisms dysfunction are reversed by atorvastatin or metformin in animals with estrogen deficiency state

I. F. Caliman1, P. W. Oliveira1, A. Z. Lamas1, S. G. Figueiredo1, P. L. Dalpiaz1, G. J. Sousa1, N. S. Bissoli1

Proc 37th IUPS (2013)

Kv7 channels are major determinants of basal coronary flow and active response to ischemia

S. Khanamiri1, E. Soltysinska1, T. A. Jepps2, B. H. Bentzen1, P. S. Chadha2, N. Schmitt1, I. A. Greenwood2, S. Olesen1

Proc 37th IUPS (2013)

Cardioprotection from cold stress and subsequent fatty diet is mediated by Epac-1 in the isolated mouse heart

F. Edland1

Proc 37th IUPS (2013)

Flow-mediated outward remodeling and NO-dependent dilation of resistance arteries are both determined by sex and age with a key role of timing in estradiol replacement therapy

K. Tarhouni1, A. Guihot1, L. Grimaud1, B. Toutain1, L. Loufrani1, F. Lenfant2, J. Arnal2, D. Henrion1

Proc 37th IUPS (2013)

The effect of l-arginine on microvascular reactivity in normotensive subjects with family history of hypertension

Z. Melik1, P. Zaletel1, T. Virtic1, K. Cankar1

Proc 37th IUPS (2013)

Improvement of blood-retinal barrier breakdown in type 2 diabetic rats by alpha-mangostin

C. Areebambud1, C. Mekseepralard2, A. Jariyapongskul1

Proc 37th IUPS (2013)

Neuropilin-1 regulates endothelial focal adhesion turnover via p130Cas phosphorylation.

I. Evans1, W. Pickworth1, G. Schey1, P. Frankel1, I. C. Zachary1

Proc 37th IUPS (2013)

The role of Na+/H+ exchanger-1 during ischemia-induced cerebrovascular dysfunction

Y. Jung1

Proc 37th IUPS (2013)

Assessment of arterial distensibility in patients with sarcoidosis

H. Balci1, S. Sipahi Demirkok2, M. Yildiz3, G. Metin3, M. Hacibekiroglu1, G. Simsek3

Proc 37th IUPS (2013)

Increased permeability of pulmonary arterioles after cardiopulmonary bypass.

T. Beleznai1, L. Walker2, R. Ascione2, K. A. Dora1

Proc 37th IUPS (2013)

Peripheral circulatory changes during Valsalva maneuver using DC component of Photoplethysmographic signal

D. S. Chandran1, A. J. Kattoor1, A. K. Jaryal1, K. K. Deepak1

Proc 37th IUPS (2013)

Aliskiren associate with L-Arginine improves vascular reactivity of renovascular hypertension rats

C. Santuzzi1, R. V. Tiraddentes1, V. Mengal1, H. Mauad1, P. Matos1, S. A. Gouvea1, M. H. Cunha1, G. R. Abreu1

Proc 37th IUPS (2013)

Pharmacological analysis of sympathetically-mediated constriction in wild type and +

C. Stevenson1, C. Daly1, E. McLachlan2, I. McGrath1

Proc 37th IUPS (2013)

Mathematical modelling of capillary O2 supply capacity in cardiac and skeletal muscle

A. A. Al-Shammari1, E. A. Gaffney1, S. Egginton2,3

Proc 37th IUPS (2013)

The effects of Insulin-like Growth Factor Binding Protein-1 on endothelial repair in the insulin resistant setting

A. Aziz1, N. Yuldasheva1, J. Smith1, N. Haywood1, P. Cordell1, R. Cubbon1, K. E. Porter1, M. T. Kearney1, S. B. Wheatcroft1

Proc 37th IUPS (2013)

Tissue- and agonist-specific isolated murine arterial responses to ageing.

C. Nicholson1, M. Sweeney1, S. C. Robson1, M. J. Taggart1

Proc 37th IUPS (2013)

Curcumin could ameliorate diabetic vascular inflammation by decreasing ROS overproduction, leukocyte-endothelium interaction, and NOX2 expression

N. Wongeakin1, P. Bhattarakosol2, S. Patumraj1

Proc 37th IUPS (2013)

Apocynin prevents vascular effects caused by chronic exposition to low concentrations of mercury

J. T. Dini1, D. Rizzetti1, F. Maciel Peçanha1, D. Valentim Vassalo1, G. Wiggers1

Proc 37th IUPS (2013)

Sulforaphane pre-treatment reduces Nrf2 content in core and peri-infarct brain regions in rats subjected to ischaemia-reperfusion injury

S. Srivastava1, A. Alfieri1, R. C. Siow1, P. A. Fraser1, G. E. Mann1

Proc 37th IUPS (2013)

Interaction of Sequestosome1/p62 with voltage-activated potassium channels in arterial smooth muscle cells in injury-induced arterial remodeling

T. Ishii1, E. Warabi1, R. C. Siow2, G. E. Mann2

Proc 37th IUPS (2013)

Inhibitory Effects of Sprouty4 on proliferation and migration of vascular smooth muscle cells involving in suppression of MAPK and Akt double signal pathways

H. Li1,2, X. Yang2, R. Liaw2, Y. Shi3, S. Ma4, B. Friesel2

Proc 37th IUPS (2013)

TRPV1 and autocrine serotonin signalling elicit Ca2+ release from the acidic organelles of ADP-stimulated human platelets.

S. Sage1, A. Harper2

Proc 37th IUPS (2013)

Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca2+-sensitive K+ channels in rat mesenteric artery

O. Roberts1, T. Kamishima2, R. Barrett-Jolley3, J. M. Quayle2, C. Dart1

Proc 37th IUPS (2013)

Role of Nitric Oxide in the control of the SR Ca2+ release in myocytes of arteriolar networks in situ

L. Borysova1, S. Wray1, D. A. Eisner2, T. Burdyga1

Proc 37th IUPS (2013)

Asthmatic cytokines IL-13 and TGF+

Y. Shaifta1, D. B. Wright1, V. Snetkov1, J. P. Ward1

Proc 37th IUPS (2013)

Mechanisms regulating localized and global calcium responses in vascular cells

N. Tsoukias1, A. Kapela1, J. Parikh1

Proc 37th IUPS (2013)

Is platelet mediated leukocyte recruitment a potential therapeutic target in atherosclerosis?

M. Harrison1, G. B. Nash1, S. P. Watson1, E. Rainger1

Proc 37th IUPS (2013)