Proceedings Abstracts of The Physiological Society

Somatosensory Physiology

Modulation of gap junction connectivity can both enhance and disrupt patterned activity within sensory networks of the spinal dorsal horn

C. W. Kay1, A. King1, E. Sher2, U. Daniel2

Proc Physiol Soc 27 (2012)

Chemerin attenuation of potentiated C-fibre input to the lamina I pain pathway

A. Dickie1, C. Torsney1

Proc Physiol Soc 27 (2012)

Assessment of myelin thickness and axon circularity in a dorsal root of the mouse

R. Durbaba1, D. Rudd1, M. Hulliger2, R. W. Banks3

Proc Physiol Soc 27 (2012)

Pre- and postsynaptic expression of long term depression at glutamatergic primary afferent synapses on dorsal horn spinal cord neurons in co-culture

S. Mariia1, F. A. Svetlana1, V. S. Nikolai1

Proc Physiol Soc 27 (2012)

Vascular endothelial growth factor splice variants VEGF165a and VEGF165b modulate spinal nociceptive processing in the rat

R. P. Hulse1,2, D. O. Bates1,2, L. F. Donaldson1

Proc Physiol Soc 27 (2012)

An ex vivo Preparation of Mouse Pinna for Recording Afferent Responses from Guard Hair Follicles of Hairy Skin

R. W. Banks1, P. M. Cahusac2, S. Watson3, G. S. Bewick3

Proc Physiol Soc 27 (2012)

A- and C- nociceptor sensitisation in acute and chronic cutaneous inflammation

R. Drake1, M. Hsieh1, B. Lumb1, L. Donaldson1

Proc Physiol Soc 27 (2012)

Descending tone in the noradrenergic system transiently suppresses ipsilateral and completely masks contralateral neuropathic pain following tibial nerve injury in rat

S. Hughes1, L. Hickey1, B. M. Lumb1, A. E. Pickering1

Proc Physiol Soc 27 (2012)

Vinblastine-induced axoplasmic transport disruption of the rat sciatic nerve causes behavioural changes consistent with neuropathic pain

K. G. Pulman1, N. Richards1, A. Dilley1

Proc Physiol Soc 27 (2012)

TRPV1 is modulated by VEGF in an isoform and PKC dependent manner

J. Prager1, N. Beazley-Long1, L. F. Donaldson1, D. O. Bates1

Proc Physiol Soc 27 (2012)

Cortical reorganization in elite athletes: lessons in plasticity for brain injury treatment

D. Hoad1,2, L. Desikan1,2, P. Flanagan1, S. Shribman1, P. Hammond1, R. Greenwood1,2, J. Rothwell1

Proc Physiol Soc 26 (2012)

Possible nerve inflammation in patients with diffuse chronic pain syndromes

A. Dilley1, J. Greening1

Proc Physiol Soc 23 (2011)

CCL2 excites a subgroup of inflamed C-fibre axons in the rat

N. Richards1, A. Dilley1

Proc Physiol Soc 23 (2011)

The gap junction opener trimethylamine enhances characteristics of network based activity within nociceptive dorsal horn

C. Kay1, D. Ursu2, E. Sher2, A. King1

Proc Physiol Soc 23 (2011)

Selective decline in slowly adapting type I mechanoreceptors during development in rat sinus hair follicles in vitro

P. M. Cahusac1, S. Senok2

Proc Physiol Soc 23 (2011)

Skin stretch at the human wrist reduces the accuracy of tactile distance discrimination.

F. Cody1, A. Ali1, Y. Gbejuade1, D. Lloyd2

Proc Physiol Soc 22 (2011)

Chronic inflammation increases hyperpolarization-activated current in C-, but not A??-, fibre nociceptive neurons in rats in vivo

X. Weng1, L. Djouhri1

Proc Physiol Soc 22 (2011)

Chronic hindlimb inflammation increases excitability of C-, but not A??-, fibre nociceptive neurons in rats in vivo

L. Djouhri1, X. Weng1

Proc Physiol Soc 22 (2011)

Expression of N-acyl phosphotidylethanolamine phospholipase D in rat dorsal root ganglion neurons

J. Valente1,4, H. Tailor1, A. Jenes1, K. Mackie2, F. Cravatt3, L. Buluwala1, A. Avelino4, I. Nagy1

Proc Physiol Soc 22 (2011)

Chronic inflammation increases expression of hyperpolarization-activated and cyclic nucleotide-gated channel subunit 2 in small dorsal root ganglion neurons in the rat

T. M. Smith1, L. Djouhri1

Proc Physiol Soc 22 (2011)

The physiological basis of acid insensitivity in the African naked mole rat

E. St. John Smith1, D. Omerbasic1, G. Anirudhan1, S. G. Lechner1, G. R. Lewin1

Proc Physiol Soc 21 (2010)

Defining the forces required to gate mechanosensitive channels in mammalian sensory neurons

K. Poole1, G. R. Lewin1

Proc Physiol Soc 21 (2010)

Heritability of mechanosensory traits in humans

H. Frenzel1, J. Bohlender2, K. Pinsker2, M. Gross2, G. R. Lewin1

Proc Physiol Soc 21 (2010)

Deconstructing Pain and Touch Sensation with Caenorhabditis elegans

M. B. Goodman1

Proc Physiol Soc 21 (2010)

Activation of the MAP-Kinase signalling pathway and Fos expression by Neurokinin-1 and NMDA receptors in rat trigeminal nucleus caudalis in-vitro: mechanisms of trigeminal pain

T. Aggarwal1, C. E. Allen2, M. A. Worsley2, A. Billinton3, F. M. Boissonade2, A. E. King1

Proc Physiol Soc 19 (2010)

Inflammation-induced increase in hyperpolarization-activated current (Ih) in C-fibre nociceptive dorsal root ganglion neurons in rats in vivo

X. Weng1, L. Djouhri1

Proc Physiol Soc 19 (2010)

Transformation in the Neural Code for Whisker Deflection Direction

M. R. Bale1, R. S. Petersen1

Proc Physiol Soc 19 (2010)

Investigating the involvement of gap junctions in patterned activity within sensory networks of the spinal dorsal horn: a study using a multi-electrode array technology

C. W. Kay1, R. J. Chapman1, D. Ursu2, E. Sher2, A. King1

Proc Physiol Soc 19 (2010)

An investigation on the analgesic effects of oxytocin in mice model of painful diabetic neuropathy

M. Ozcan1, A. Ayar2, E. Alcin3, I. Serhatlioglu1, S. Ozcan4, S. Kutlu3, H. Kelestimur3

Proc Physiol Soc 19 (2010)

Immunogold labelling for glutamate in lanceolate endings of rat hairs.

F. C. Shenton1, H. Wollner1, G. S. Bewick2, R. W. Banks1

Proc Physiol Soc 17 (2009)

Glutamatergic modulation of vesicle turnover in primary mechanosensory endings

P. Singh1, A. Simon1, R. W. Banks2, G. S. Bewick1

Proc Physiol Soc 17 (2009)

Neurons in the rostral ventromedial medulla (RVM) that possess the NK-1 receptor contribute to descending facilitation of spinal nociceptive transmission

S. G. Khasabov1, D. A. Simone1

Proc Physiol Soc 17 (2009)

Midbrain control of spinal cold processing

J. Leith1, S. Koutsikou1, B. M. Lumb1, R. Apps1

Proc Physiol Soc 17 (2009)

Development of human infant pain behaviour: Nociceptive flexion withdrawal reflex EMG activity and facial motor responses in preterm and term infants

L. Cornelissen1, R. Slater1, S. Boyd2, M. Fitzgerald1

Proc Physiol Soc 17 (2009)

The peripheral pro- and anti-nociceptive effects of galanin are mediated by activation of GalR2

R. Hulse1, D. Wynick1, L. Donaldson1

Proc Physiol Soc 17 (2009)

Responses of lamina I NK1 receptor-expressing projection neurons and interneurons to noxious stimulation

K. S. Al Ghamdi1, E. Polgár1, A. J. Todd1

Proc Physiol Soc 17 (2009)

The accuracy of tactile localization is reduced by skin stretch at the human wrist

F. Cody1, R. Idrees1, D. Spilioti1, E. Poliakoff2

Proc Physiol Soc 17 (2009)

Transformation in the neural code for whisker deflections from receptors to cortex

M. Bale1, R. S. Petersen1

Proc Physiol Soc 17 (2009)

Mechanisms of TRPV1-mediated desensitisation of the nociceptive ion channel, TRPA1

C. Doran1, G. Reid1

Proc Physiol Soc 17 (2009)

Substance MCS-18 from Helleborus purpurascens inhibits capsaicin and acid induced activation of TRPV1

C. Neacsu1, A. C. Ciobanu1, O. Toader1, G. Szegli2, F. Kerek3, A. Babes1

Proc Physiol Soc 17 (2009)

Are the projections from the periaqueductal grey to pontine noradrenergic neurones excitatory or inhibitory?

L. Hickey1, E. Sher2, B. Lumb1, A. E. Pickering1

Proc Physiol Soc 15 (2009)

Acute and chronic effects of GDNF and BDNF on thermoTRPs from rat dorsal root ganglion (DRG) neurons

C. Ciobanu1, A. Babes1, G. Reid2

Proc Physiol Soc 15 (2009)

Activation of the capsaicin receptor TRPV1 desensitises the nociceptive ion channel TRPA1 in rat dorsal root ganglion neurones

C. Doran1, G. Reid1

Proc Physiol Soc 15 (2009)

P2Y activation affects the excitability of murine epidermal primary afferents through modulation of the Kv7-mediated M-current

G. Bruce1, R. Barrett-Jolley1, R. Morris1

Proc Physiol Soc 15 (2009)

KCa channels regulate stretch-evoked afferent firing from muscle spindles.

A. Simon1, R. W. Banks2, G. S. Bewick1

Proc Physiol Soc 15 (2009)

Descending modulation of cool- and cold-evoked spinal nociception by the periaqueductal grey.

S. Koutsikou1, L. Leith1, B. Lumb1, R. Apps1

Proc Physiol Soc 15 (2009)

Stimulation of the periaqueductal grey modulates cortical somatosensory evoked potentials elicited by an acute noxious stimulus.

E. K. Davies1, S. Koutsikou1, B. M. Lumb1, J. C. Murrell2

Proc Physiol Soc 15 (2009)

Oxytocin provokes increase of free intracellular Ca2+ levels in freshly isolated rat sensory neurons

M. Ozcan1, S. Kutlu2, E. Alcin2, B. Yilmaz3, H. Kelestimur2, A. Ayar4

Proc Physiol Soc 15 (2009)

Spinorphin Inhibits Membrane Depolarisation-Induced Intracellular Calcium Signals in Cultured Rat Dorsal Root Ganglion Neurons

A. Ayar1, M. Ozcan2, T. Kuzgun3, E. Alcin2

Proc Physiol Soc 15 (2009)

Inflammatory mediator-evoked transcriptional changes in the TRPV1 splice variant, TRPV1b, in cultured primary sensory neurons

S. Mistry1, C. C. Paule1, A. Photiou2, L. Buluwela2, A. Avelino3, C. Raguenga3, A. Charrua3, F. Cruz3, I. Nagy1

Proc Physiol Soc 12 (2008)