R Jean Banister Prize Lecture: Dr Bethan Phillips of the University of Nottingham - “Physiological adaptations to traditional and novel exercise interventions as a function of age”

24 May 2019

University of Derby, Derby, United Kingdom

About the R Jean Banister prize lecture:

This is one of The Society’s prestigious prize lectures and was established in 2016 in memory of Professor (Rachel) Jean Banister (1917-2013). It is an annual series of peripatetic lectures given by an early career scientist on any physiological topic. 

2019 Lecture overview:

“Physiological adaptations to traditional and novel exercise interventions as a function of age”:

Beth Phillips is an Assistant Professor of Clinical, Metabolic and Molecular Physiology in the School of Medicine at the University of Nottingham. Since graduating in Sport & Exercise Sciences from Loughborough University and then completing her PhD at the University of Nottingham, Beth’s research has focussed on the pathophysiology of age-associated musculoskeletal morbidities (sarcopenia, cachexia, disuse, metabolic syndrome etc.) and interventions to mitigate their progression and consequences. Combining molecular biology, stable isotope methodologies and detailed in vivo human physiology, Beth has been a key part of a team that has uncovered fundamental parameters governing alterations in musculoskeletal metabolism with ageing and disease. Specifically, one unique aspect of Beth’s research expertise is combining detailed in vivo human physiology with state-of-the-art vascular imaging methodologies to determine links between the musculoskeletal microvasculature and metabolic dysregulation in ageing and disease, and in the context of exercise-, pharmacological- and nutrition-based interventions. Latterly, Beth’s focus has been exploring the basis for heterogeneous metabolic and physiological alterations in response to traditional and novel “exercise-for-health” interventions, in both healthy and clinical cohorts. In this lecture, Beth will present a composite of recent work from her group, including exploring the heterogeneous efficacy of resistance exercise training, high-intensity interval training, remote ischaemic pre-conditioning and isometric handgrip training in various groups, including cancer patients, with discussion of potential metabolic mechanisms limiting adaptive capacity.

Dr Beth Phillips