Post Doc position

Location

Ribeirão Preto Medical School, Ribeirão Preto
Closing date: 
30 September 2018
Contact: 
Rodolfo Borges dos Reis

Postdoc Researcher in mitochondrial genomic of renal tumors

São Paulo Research Foundation FAPESP São Paulo, Brazil.

Description:

A postdoctoral position is available at the Laboratory of Uro-Oncology directed by Professor Rodolfo Borges dos Reis, Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. The candidate must hold a Ph. D. Interpersonal skills, oral and written communication, analytical skills, creativity and initiative are essential requirements. The objective of the project to be conducted involves evaluation of the heterogeneity of the mitochondrial genome of mitochondria extracted from clear cell renal carcinoma. Mitochondria will be isolated from tumoral tissues to avoid contamination of mitochondrial pseudogenes present in the nuclear DNA. The parameters to be evaluated involve mitochondrial DNA depletion,taking into account the determination of copynumber by the qPCR; and also the evaluation of the rearrangements (deletions) and the complete sequencing of the mitochondrial genome in large-scale genomic (NGS).

Profile:

The candidate must hold a Ph. D title with emphasis in urology, or related Disciplines (the Ph. D title cannot have been obtained more than two years from the application deadline). It is emphasized that knowledge of renal anatomy and histology are required, besides the experience with techniques relevant to the proposal of new generation sequencing tools for conducting mitochondrial genome isolation and extraction;experience with real-time PCR (qPCR), conventional PCR, NGS library preparation for Ion Torrent PGM and manipulation of bioinformatics data of the mitochondrial genome (will be considered strong differentials) are also required as well. In addition, the candidate must have previous experience for collecting, transporting and storing human biological material obtained from surgery.

How to Apply:

The candidate must applybefore September 30th, 2018. The documents required are the following: Curriculum Vitae; three names or letters of references; copy of the Ph. D degree or a statement of the date when the Ph. D. title was obtained, to the e-mail of Professor Rodolfo Borges dos Reis, M.D., Ph.D. (rodolfosbusp@uol.com.br) [Department of Surgery and Anatomy, Ribeirão Preto Medical School, 3900. BandeirantesAvenue, 14049-900, Ribeirão Preto, SP, Brazil].