PhD in Pain Research


The School of Life Sciences, Coventry
Closing date: 
14 February 2019
Prof Bruno Frenguelli

Fully funded studentship available for entry in September 2019 

Title: Development of novel Purine-based analgesics 

University of Warwick and Industry Supervisors: Prof. Bruno Frenguelli and Dr Mark Wall (University of Warwick) and Prof. Dave Spanswick (NeuroSolutions Ltd) 

Project summary 

Pain is a common condition that can be extremely debilitating for chronic sufferers. While a wide range of analgesics (compounds that provide pain relief) are available, not all analgesics are suitable for all types of pain and opioid analgesics can cause dependence. New analgesics are therefore needed. Adenosine is a neurotransmitter in the central and peripheral nervous systems that has analgesic properties. In collaboration with leading pain specialists at Neurosolutions Ltd and colleagues at the Universities of Bern (Switzerland) and Cambridge (UK) this project will explore novel compounds targeting adenosine receptors for their potential as new classes of analgesics. 

Through this project the successful student will gain excellent academic, technical and transferable skills in neuroscience, pain physiology and pharmaceutical drug discovery.

About the Program: This Industrial Collaborative Award in Science and Engineering (iCASE) studentship is offered by Warwick’s MRC Funded Doctoral Training Partnership (DTP). This training program involves an exciting one-year MSc in Interdisciplinary Biomedical Research and then a three-year PhD project which is co-supervised by experts from both academia and industry. The student will benefit from a comprehensive training program that offers advanced workshops, career planning, transferable skills training and cohort learning events and conferences with ~ 50 other PhD students.