I am one of three theme leads for the Cardiac and Vascular Physiology Theme. My research interests are in cardiac cellular physiology and the mechanisms underlying conditions such as heart failure and arrhythmias. Cardiovascular diseases remain a major cause of mortality, accounting for 160,000 deaths per year in the UK alone. This Theme encompasses all aspects of this vast research field from cellular to organ level and the integration of functions to produce appropriate cardiovascular responses. As Sarah Calaghan and I outlined in our article in the Spring 2018 edition of Physiology News as leads to the previous Cardiac and Respiratory Physiology theme, with increasing access to gene editing and super-resolution imaging technologies, now is an exciting time to be a physiologist.