Paul Le Tissier

Senior Lecturer, University of Edinburgh

I received my PhD from Reading University in 1990 and worked as a post-doctoral researcher at the University of Sydney and the National Institute for Medical Research (NIMR) in London. I spent a year as a Senior Scientist at the University of Manchester before taking on my current role as a Senior Lecturer at the University of Edinburgh, where I’ve worked since 2014.

My principal research interest looks at how the different cell populations of the anterior pituitary gland function to maintain and alter their output throughout life and how their dysregulation leads to pathology. The anterior pituitary gland is an important regulator of many physiological processes, controlling growth, reproduction, lactation, metabolism and stress. In different physiological states (puberty, pregnancy, lactation, etc) both the amount and pattern of hormone output change and a combination of these determines how target organ function is modified in response to hormone stimulation. I use an integrated approach, from the level of individual cells and their organisation to their secretory activity and its effect on whole animal physiology. Currently my research focuses on three main areas: (1) plasticity and organisation; (2) monitoring secretion; and (3) pathology.

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