Localization of cortical areas activated by visual memory task using functional magnetic resonance imaging

37th Congress of IUPS (Birmingham, UK) (2013) Proc 37th IUPS, PCD116

Poster Communications: Localization of cortical areas activated by visual memory task using functional magnetic resonance imaging

A. Sokolov1, V. Fokin1, E. Aleksandr1, S. Vorobyev2

1. Radiology, Medical Military Academy, Saint-Petersburg, Russian Federation. 2. Neurology, Medical Military Academy, Saint-Petersburg, Russian Federation.

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Purpose: To localize cortical areas activated by visual memory tasks by the mean of functional magnetic resonance imaging (fMRI). Methods: We used 1.5 T MR-scaner and BOLD-method (Blood Oxygenation Level Dependent), based on distinctions of magnetic properties of hemoglobin. We studied 27 healthy volunteers (20-32 year old). All of them passed MMSE, FAB, CES-D, attention and memory tests. There were done anatomical and fMRI fast imaging technique: echo planar imaging (EPI), whole brain scan (36 slices) matrix 64×64, 3.7 second. Fast imaging technique on modern MR-scanners with ≥ 1.5 T provides precise statistical maps of oxygenation increase with high spatial resolution. SPM8 software package was used for fMRI assessment and statistical analysis. For test stimuli we used series of 12 not related images for “baseline” and 12 images with 6 presented before for “active”. Stimuli were presented 3 times with reduction of repeated images to 4 and 2. Results: the investigation showed bilateral activity of anterior cingulate gyrus in 90% cases. In 70% cases activity was evidenced in parahippocampal gyrus (bilateral – 20%, left parahippocampal gyrus – 70%). We also noted activation of superior frontal gyrus (Brodman area 6 – BA6) in 45% cases, BA 21, 37, 38 in 40% cases. Conclusion: our data are well co-coordinated with neurophysiologic and clinical findings that several brain areas are involved in realization of visual memory tasks. Visual memory is provided by integrative processes in brain cortex. These data will be able to use in clinical practice in patients with cognitive disorders.



Where applicable, experiments conform with Society ethical requirements.

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