Older men exhibit a preserved vascular conductance (VC) response to incremental leg extension exercise compared to active young men1. However, the age-related effects on the rate at which the leg vascular conductance response increases at the onset of constant load exercise (VC kinetic response) has not yet been examined. To examine the vascular conductance kinetics response during calf constant-load plantar-flexion exercise performed at different intensities in older and younger men Thirteen older (60-84 years) and thirteen younger (20-30 years) sedentary men were tested. Ethical approval was obtained from the Trinity College Dublin Faculty Research Ethics Committee. Subjects performed three constant load exercise bouts (6 min long) of intermittent calf plantar flexion exercise (6s duty cycle: 2 s contraction, 4 s relaxation) at an intensity of 30% maximum voluntary contraction (MVC) on a custom-built calf ergometer at a tilt of 67 degrees. This was then repeated at an intensity of 45% MVC. Calf BF was measured contraction by contraction using venous occlusion plethysmography. Kinetic analysis was performed by fitting a biexponential function to the mean (3 bouts) of the vascular conductance (BF/MAP) data. Student t- tests were used to detect differences between groups. Results are depicted as mean ± SD. The time constant of the fast component was significantly shorter in the young (30% ; 19.3±16s: 45%; 37.5 ±13.20) compared to the older (30% ;82.2 ± 8.6s :45%; 54.3±48.7) group but the rest of the VC kinetic parameters, the mean response time and the end exercise amplitude at 360s were not different between both groups. This study showed that the rate at which vascular conductance responses increase during constant load static calf exercise is faster in younger men compared to older men.
University College Dublin (2009) Proc Physiol Soc 15, PC109
Poster Communications: Leg vascular conductance kinetics in older versus younger men during constant load calf plantar flexion exercise
H. N. Reilly1, M. Egana1, S. Green2
1. Physiology, Trinity College, Dublin, Ireland. 2. Physiology, University of Otago, Dunedin, New Zealand.
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Where applicable, experiments conform with Society ethical requirements.