ObjectivesOu MC decrescendo phenomenon (OuDP) is induced by interaction between human bilateral features and has shown to alleviate or cure infections and non-infectious diseases. The resolution of non-infectious disease with OuDP is consistent with the restoration of normal tissue function. The previous study showed that OuDP ameliorates degenerative diseases (Proc Physiol Soc, 2014; NS, 2014). This study is to further approach the mechanism of OuDP with the cases of human oncologic diseases.MethodsOu MC handing remedy (HR) was availed to induce OuDP with hand to contralateral body part (AJEM, 2012; Proc Physiol Soc, 2014). Four female patients received HR for their oncologic diseases. Case 3 was treated with oral ergonovine maleate and tranexamic acid for the initial 5 days of HR treatment and case 4 had undgone treatment with Glivec for 2 years, while The other 2 patients have not received other treatments (Table 1). Though complementary therapy is exempt from informed consent by the law in Taiwan (Department Health, ROC. (1993) No.82075656), all patients agreed and provided consent for participation in this study.ResultsThe OuDP showed to ameliorate oncologic changes of the four patients (Table 1). The uterine endometrioid cancer regressed from stage IIIB to IA with 5 months HR. The pancreatic isodense lesion of suspicious pancreatic cancer decreased from 1.6. x 1.7 to 1.0 x 1.0 cm in size with CA199 descending from 1090.0 to 136.5 (Unit/ml) associating with the main pancreatic duct diameter decreasing from 0.39 to 0.14 cm with tortuosity disappearance after 4 months treatment. (Fig. 1) The frequent profuse bleeding by uterine leiomyosarcoma prominently decreased immediately with HR and subsequent HR was also effective at minimizing heavy uterine bleeding in 3 weeks treatment. The gluteal macular lesion with chronic myeolgenous leukemia eliminated after 2 weeks treatment with HR. (Proc Physiol Soc, 2014, NS, 2015).ConclusionsIt reveals OuDP may normalize the tumor cells and microenvironmental function, which makes tumor cells conform to the regulations with apoptosis, metastasis suppression, preventing uninhibited proliferation, and supervision by host immunological systems.