Higher magnitude of adiposity, abdominal obesity and a lower muscle mass vis-à-vis body mass index (BMI) as compared to white Caucasians and significant positive association of BMI and body fat with blood pressure are reported in indians (1).Studies exploring baseline blood pressure and pressor response to isometric exercise in indian (muslim) girls with restricted outdoor activities and physical exercise are scanty. Ninety female muslim medical students(18-22yrs) of identical ethnicity and socio-economic status were administered a detailed questionnaire and signed informed consent was obtained as per Helsinki declaration. They were divided into non-obese group (BMI<25,n=66),overweight(BMI≥25-<30) and obese (BMI ≥30) groups, clubbed together(n=24). After recording baseline diastolic (DBP) and systolic blood pressures(SBP) , they performed isometric exercise (Hand grip dynamometer test, HGT) at 30% of T max value, and SBP and DBP were recorded at 1, 2 and 3 minutes of exercise. Our results indicated higher incidence of obesity (25%) and hypertension(12.5%) than reported[15%(2,3)and 12% (2,4) respectively].Statistical analysis by student’s T-test at 95% confidence level (paired and independent sample comparison, P<0.05) revealed the baseline DBP , SBP and SBP at 2 and 3 minutes of HGT to be significantly higher in the obese group ( P<0.002,0.003, <0.04 and <0.007 respectively) that correlated positively with BMI(Pearson correlation, r=0.4,0.4,0.32 and 0.35 respectively, P<0.001).Using OMRON body fat analyser (HBF-362 Karada scan, based on bioelectrical impedance analysis), total body fat (TBF%),Visceral fat (VF, number) and body/ biological age (BA)were obtained. All the values are means ± S.E.M., compared by ANOVA. Significant increases (P<0.001) in body age (41.0±1.17vs23.39±0.68), TBF% ( 36.2 ± 0.7vs 27.0 ±0.5 ) and VF(9.58±1.1 vs 2.48±0.15) were observed in obese students. Significant (P<0.01) positive correlation between TBF% vs body age (r=0.9), VF vs body age( r=0.88) and TBF % vs visceral fat (r=0.8) and significant linear relationship with BMI (linear regression analysis, P<0.01, R= 0.95,0.89 and 0.95 respectively) were observed. Surprisingly, in 50% of the control group with normal BMI(<25,n=33), having total body fat% greater than normal (>28%), the body age was significantly higher( 27.6±0.8vs19.18±0.36,P<0.03) than rest of the controls. Biological age defines how time and lifestyle have affected organs and cells and includes changes in the physical structure of the body, performance of motor skills and sensory awareness as compared to other people of similar chronological age (5). Higher body age and total body fat% can lead to cardiovascular ailments and morbidity even if BMI is within normal limits and hence should be considered while classifying obesity.
Physiology 2016 (Dublin, Ireland) (2016) Proc Physiol Soc 37, PCA158
Poster Communications: Pressor response to isometric exercise and correlation of body mass index, total body fat, visceral fat and body age in obese and non-obese female medical students
S. Kalluri1, S. E1, V. G3, P. R2
1. Physiology, Drvrk Women's Medical College, Hyderabad, Telangana, India. 2. Community Medicine, Drvrk Women's Medical College, Hyderabad, Telangana, India. 3. Department of Physiology, Kamineni Academy of Medical Sciences, Hyderabad, Telangana, India.
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