Progressive resistance exercise training (RE-T) is known to enhance muscle mass and function in both young and older individuals (1); thereby providing a myriad of health benefits, such as decreasing the risk of diabetes, cardiovascular diseases and/ or sarcopenia (2). However, achieving compliance with regular RE-T can be difficult due to perceived and real socio-economic, psychological and environmental factors e.g. access to specialised equipment (3). Therefore, there is significant need for the development of alternative RE-T programmes to try and alleviate these barriers to exercise, in order to provide a widely-accessible intervention that can deliver the associated health benefits of RE-T to a wider population (4). This study aimed to assess the efficacy of 4-weeks home-based RE-T, fully integrated into activities of daily living, on leg lean mass and physical function. Twelve healthy older volunteers (63±3 y, 60:40 M:F, BMI: 29±1 kg.m-2 (mean±S.E.M.)) were recruited to this study. Before and after RE-T all volunteers performed a battery of physical function tests including: leg extension 1-RM (one repetition-maximum), a short physical performance battery test (SPPBT; assessing balance, gait speed and time to rise), lower limb power (via Nottingham power rig), handgrip strength and maximal voluntary contraction (MVC) for leg extension. Ultrasound measures were made before and after RE-T to assess quadriceps cross sectional area (CSA). For the RE-T, volunteers were provided with instructions for 8 different home-based RE-T exercises that could be incorporated into habitual activities (e.g. “toothbrush squats”, “hoover lunges”, “cooking bicep curls”). Volunteers were instructed to perform 3×12 repetitions of each exercise, every day for 4-weeks. After RE-T, despite no significant increase in 1-RM, handgrip strength or SPPBT, there was a significant (p<0.05) increase in quadriceps CSA (1.5±0.8 cm3, (mean±S.E.M., paired t-test)), MVC (14.6±7.7 Nm) and muscle power (46.8±19.8 Watts). In conclusion, this study demonstrates that RE-T fully integrated into activities of daily living has potential benefit for the maintenance of muscle mass and physical function. Home-based RE-T, such as this, i.e. an exercise intervention without the requirement of finances or access to specialised equipment, could benefit not only older individuals, and those with co-morbidities associated with loss of muscle mass (e.g. diabetes, COPD or sarcopenic/frail elderly (5)); but may help alleviate psycho-social barriers to physical activity such as, one of the most commonly cited; “lack of time” (3).