Fat oxidation rate during submaximal exercise is one of the important parameters of fitness level and is expected to be low in sedentary individuals and could be improved with training. And there is some evidence that resistance training could improve fat oxidation rate at rest. The aim of this study was to investigate the effects of progressive resistance exercises (PRE) targeting the muscles, rich in type 1 fibers, on fat oxidation rate at submaximal work rates, in young sedentary individuals. Seven sedentary volunteers (university students) recruited for this study. Their rating of global physical activity questionnaire (GPAQ) demonstrated that they were indeed sedentary individuals. All of the voluntary participants underwent an incremental cardiopulmonary exercise testing (CPET) till exhaustion using cycle ergometer. Heart rate, work load, respiratory exhange ratio (RER) and respiratory gas analysis were determined by breath by breath method. RER was used as indice to determine the fat oxidation rate. Fat oxidation rate was expressed as a percentage of the ratio of fat usage to total substrate utilization (which were calculated automatically) at the %30, %40, %50 and %60 of maximal VO2. Then the individuals performed PRE specifically targeting five muscles (namely soleus, tibialis anterior, biceps femoris, vastus medialis and adductor magnus) which known to be rich in type 1 fibers. The PRE was performed three times a week and lasted 6 weeks, then the test was repeated. The Wilcoxon test was used to evaluate pre-post training values. The basal median value of the fat oxidation rate at %30 VO2 max was % 28,5 and rised up % 44,2 but the difference was not significant (p=0,237). The median value of %40 VO2max was %17 and rised up to %24,6 after the exercise but the difference was not significant (p=0,063). The median of fat oxidation rate at %50 VO2 max was %14,1 and declined to %12,05 but the difference was not statistically significant (p=0,735). The fat oxidation rate at %60 VO2 max was % 4,94 and declined to %3,85 (p=0,499). Although the effect of PRE on fat oxidation at analysis points was not statistically signifanct , this results indicated that this kind of exercise could be benefical for fat oxidation rate while people performing the low intensity exercise at intensities around about %40 VO2 such as walking in low speed, engaging in housework. This results have some implications of hope for obese people to achieve better fat oxidation with PRE, and this topic deserve further comprehensive investigation