Ventilatory efficiency is an indicator of ventilation-perfusion mismatch at lungs. It is independent of effort and can be measured in submaximal workloads. Ventilatory efficiency which can be calculated from ventilatory equivalent for CO2 (VE/VCO2) and O2 ventilatory equivalent (VE/VO2), more sensitive to ventilatory pathologies in exercise, both increases in pulmonary and cardiac diseases. This parameters are associated with better fitness level and tend to increase as individuals get older. Although effects of aerobic exercise on parameters related to cardiorespiratory status including VE/VCO2 are documented, in this study the effect of progressive resistant exercise on muscles rich in type 1 fiber ratio (soleus, biceps femoris, adductor magnus, tibialis anterior, vastus medialis) was investigated. University students aged 19-25 filled International Physical Activity Questionnaire to confirm that they were indeed sedentary. 12-LED cardiopulmonary exercise test (CPET) was performed on bicycle ergometer with breath by breath method before the resistance training program. Then they performed 6 week of progressive resistance training targeting muscles rich in type fibers, as 3 days per week. After training VE/VO2 and VE/VCO2 at anaerobic threshold (VE/VO2@AT and VE/VCO2@AT) at CPET, calculated by V-slope method were determined. VE/VO2@AT median (IQR) value at the anaerobic threshold before the training program was 28.1 (26.9-34.3) and it changed to 31.2 (26.9-361). But this change was not statistically significant (p=0.484). The VE/VCO2 at anaerobic threshold (VE/VCO2 @AT) median (IQR) value was 33.3 (28,2-34,9) before training and it decreased to 29.1 (27,5-32,9) after training (p=0.036). This statistically significant change in VE/VCO2 at anaerobic threshold indicates that by this local exercise protocol in individuals who are elderly, dependent on bed and cannot find opportunity to perform aerobic exercise can rehabilitate and improve their general condition.