African folklore is awash with tales and proverbs e.t.c. about everyday living in Africa. These are used to teach morals and principles. Each tale or proverb is indelibly associated with a moral or principle which is easily recalled once the former is recounted. This suggests that the power of stories/proverbs in teaching is well recognized by our forbears. Folklores elsewhere share these attributes. A classical example is the so called Ondine’s curse in German mythology. This tale may be used to teach the separation of voluntary from involuntary respiration (1). In addition, the National Institutes of Health (NIH) of the United States of America has been reported to have hired a professional story teller to help teach her scientists on how best to explain their research findings to others especially students and the general public. Thus the power of tales/proverbs in enhancing teaching is becoming more recognized. However this tool has either not been used at all or rarely used in the teaching of Physiology to African students. This work will present the use of African folklore in teaching physiological principles including righting reflexes, ageing, respiratory adjustments to high altitude and other aspects of physiology. This may hopefully stimulate others to explore this powerful tool in teaching physiology or communicating their research findings to colleagues, students and the public.