Adequate nutrition is a prerequisite for normal blood cells production. Prior to early 1984 when government feeding subsidy to students in instituions of higher learning in Nigeria and centralized cafetaria system of feeding was the norm before it was abrogated, balanced diets was provided for students. Lower values of blood cells in communities in developing countries always come from populations of low socio-economic background (Ezeilo, 2002). Studies have shown that values of well nourished Africans areindistinguishable from those of Caucasians (Green and Ezeilo, 1978). This study made up of two parts I and II were carried out among 500 apparently healthy students of Igbo origin (265 males and 235 females aged 16 – 30 years)over a period of two years to compare their blood indices -haemoglobin concentration, packed cell volume, mean corpuscular haemoglobin concentration, whtie blood cells count, total white blood cell s differential count. The subjects were selected after a structured questionnaire was administered and these blood indices were determined by standard laboratory procedures with each subject serving as control and test three months later. The results showed that haemoglobin concentration decreased after three months in both Parts I and II for both the males and females when compared with the control. Packed cell volumes were reduced from 40.2 to 29.4% (Part I) and 42.6 to 30.3% (Part II). Mean corpuscular haemoglobin concentration in females dereased from 31.5 to 30.3g/dL (Part I) and 32.8 to 30.3g/dL (Part II) and for males, from 33.6 to 30.9g/dL (Part I) and 33.5 to 30.8g/dL (Part II). Total white bloodcell decreased in both Parts I and II respectively (p < 0.05). White blood cell differentials showed that neutrophil counts decreased, eosinophil increased while the rest remained the same in both parts. The ABO blood group pattern were O – 56.9%; A – 34.3%; B – 7.1%; and AB – 1.7% while for Rhesus positive, it was 94% and negative – 5%. The results for part I and II followed a similar tend. The observed differences between the controls and the tests could be attributable to the poor campus diet as the indigent student feed according to their financial capacity and from restaurants as against when the government subsidized feeding with a centralized cafetaria system, and tropical infections such as malaria known to affect blood indices negatively. These data could serve as standard blood values for a university medical centre and to evaluate blood group situation in sourcing blood donors in emergencies. It is suggested the re-introduction of centralized cafetaria system and perhaps will enhance a better blood indices pattern