Inadequate sleep and poor sleep quality has been associated with stress, anxiety, depression, increased risk of heart disease, diabetes and overall mortality. We aimed to evaluate the self-reported sleep quality among parental caregivers of children with physical disabilities. A total of 30 female parental caregivers of children with spastic cerebral palsy (CP, mean age: 34.8±7.2 years) receiving special education school-based physiotherapy and 20 female parents of typically developing children as control group (mean age: 36.3±6.6 years) were recruited. Sleep quality was assessed by the Pittsburgh Sleep Quality Index (PSQI), including subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleeping medications, and daytime dysfunction with scores ranging from 0, no problems in area, to 3, high problem. Total sleep quality score was ranged from 0 (good sleep quality) to 21 (poor sleep quality). Data are expressed mean ± SD. Statistical analyses were performed with the use of Mann Whitney U test. Differences were considered to be statistically significant at p < 0.05. Parental caregivers of children with spastic CP had significantly poorer total PSQI score compared to controls (mean PSQI total for patients’ (n=30): 8.1 ± 4.4 vs. control parents: 3.81 ± 2.81 (22), P<0.001). Regarding the subscales of PSQI, caregivers of children with CP had significantly increased time to fall asleep on going to bed (P<0.05), significantly higher sleep disturbances (P<0.05) and significantly higher daytime dysfunction (P<0.001). A significant percent of the caregivers rated good level of satisfaction from the physiotherapy received. Our results indicate that parental caregivers had significantly poorer total sleep quality ratings and this may present a risk on their health-related quality of life. Future studies with larger samples are needed for firm conclusions on sleep quality, and sleep related quality of health of the care giving parents of handicapped children.