Invironmental light intensity affects the nervous system and is a powerful modulator of behavior. Light-intensity-dependent activity is observed in a subset of retinal output cells, which innervate a newly discovered nucleus of the dorsal thalamus, that in turn projects to the prefrontal cortex and striatum. Silencing the transmission along this pathway has been shown to affect mood. I will describe the retinal networks responsible for the transmission of light intensity signals, and show new results demonstrating the capacity for light-intensity encoding in diverse brain regions.
Sensory Signals (The Royal College of Physicians, London, UK) (2022) Proc Physiol Soc 50, SA15
Research Symposium: Retinal and brain circuits transmitting light intensity signals and regulating mood
Shai Sabbah1
1Shai Sabbah, Jerusalem, Israel
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Where applicable, experiments conform with Society ethical requirements.