Their electrotonic compactness and small number of excitatory synaptic inputs make cerebellar granule cells an attractive model system for examining temporal integration and gain modulation at single synapses. Recently, in vivo whole-cell recordings from the smallest of cells in the brain are beginning to elucidate fundamental mechanisms of sensory signaling through individual synapses in these cells. Using vestibular stimulation that is a highly quantifiable and intensity-varying stimulus, we have explored information transmission through single synapses in ketamine/xylazine-anaesthetised mice. Our data provide a realistic estimate of the number of synapses required for accurate stimulus reconstruction, and have important implications for the organizing principles underlying information transmission through the cerebellum.