Dr Jere Holloway Mitchell, a cardiologist and an internationally recognised expert on exercise physiology, died on 17 July 2021 in Dallas, Texas. Mitchell trained in cardiovascular physiology at the National Heart, Lung, and Blood Institute at the National Institutes of Health in Maryland, US. He then spent almost six decades at the University of Texas Southwestern Medical Center, US, where he served two terms as the Chief of Cardiology.

Mitchell was the architect of the landmark Dallas Bedrest and Training Study, which transformed healthcare. Understanding how the human body adapts to bedrest and exercise led to the modern practice of getting patients out of bed and increasing their mobility as soon as possible after heart surgery.

His ground-breaking research on the impact of exercise on the human circulatory system awarded him the highest honours from several societies. He received the Young Investigator Award and the Distinguished Scientist Award from the American College of Cardiology, the only recipient of both awards. He was awarded the Paton Prize from The Physiological Society, the Carl J. Wiggers Award from the American Physiological Society and received the Honour Award from the American College of Sports Medicine.