Practical demonstration by teachers has been practiced in a medical institute. It is quite difficult to handle and to involve hundred students in the laboratory exercise (Labex) at a particular time. So, practical demonstration class has been practiced in basic medical science discipline (BMSD) to tackle and minimize time and number of students in a labex. But, do practical demonstration class help medical students to develop their skill domain have been questioned by many students and teachers in the institute. So, we aimed to evaluate the importance and efficiency of practical demonstration classes in the institute. It was a cross sectional descriptive study. Pretested structured questionnaire having both open and close ended questions were administered to MBBS students (n=63) and basic medical science (BMS) teachers (n=24) and their perception were assessed. Data were expressed in frequencies. On the present scenario, both teachers (24/24) and students (57/63) believed that practical demonstrations were very helpful to student for developing their practical skills. Although most of the students (57/63) and all the teachers (24/24) were satisfied with the lab exercise (Labex) but both gave mixed response on the practical class. Most of the students (53/63) and teachers (17/24) felt and suggested that practical should be demonstration by teachers’ followed by practical work by the students, and some of them (students= 8/63 and teachers= 3/24) suggested practical work (Labex) should be briefed and done by the students followed by a feedback. Almost all the teachers (21/24) responded that they clarify queries raised by the students in the Labex. However, students mention that queries were clarified in few practical classes of BMS disciplines like in anatomy (63/63), biochemistry (61/63) and microbiology (60/63) but in physiology (22/63), pathology (28/63) and pharmacology (37/63) disciplines the clarification of queries perceived by the students was less. Regarding training on the questions and exam pattern, overwhelming majority of teachers (20/24) agreed to provide training and majority of students (51/63) want to receive the training. Thus, for the effective students’ skill development, practical classes (Labexes) should not be limited to only demonstration by teachers but it should also be done by the students. Moreover, for skill improvement, queries raised during labex should be solved on the spot by the teachers, and it will be more understandable when students involves in practical work, so that students knows how to troubleshoot the problem when they encounter the problems.