Coupling between apical and basolateral membrane ion transport in the kidney proximal tubule: role of cellular Call, pH, ATP and volume – Raynald Laprade (p.21)

The proximal convoluted tubule is the nephron segment which is responsible for the reabsorption of nearly all the filtered bicarbonate, glucose and amino acids, and more than 40% of the filtered fluid, sodium, chloride and phosphate.