Physiology as a discipline benefits from practical classes to bolster theoretical teaching. However, with ever increasing class sizes, budget considerations and the limitation of laboratory space in a central London University we face a growing challenge to deliver high quality physiology teaching in our undergraduate and postgraduate courses. In this paper, we address some of the specific solutions we have reached in the Physiology department at King’s College London at to deliver and assess an engaging, integrative and manageable human physiology practical programme.We introduce the use of web-based tutorials to aid students’ understanding of data capture, analysis and presentation and interactive physiology practical classes which re-enforce the classroom-based theoretical learning and allow students to progress at their own rate and in their own time. Overall, we believe we have demonstrated that the use of these resources enhance student engagement and increase satisfaction among undergraduate and postgraduate physiology students.