The terms ‘antioxidant’, ‘oxidative stress’, and ‘oxidative damage’ are widely used but rarely defined. I will attempt to define what they mean, and examine the ways in which oxidative stress can affect cell behaviour and the relevance of this to human diseases, taking cancer as an example. Oxidative stress can also affect cells grown in culture, sometimes leading to over-estimation of the physiological relevance of events observed in cultured cells.
Life Sciences 2007 (2007) Proc Life Sciences, SA205
Research Symposium: Biochemistry of oxidative stress
B. Halliwell1
1. National University of Singapore, Singapore , Singapore.
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Where applicable, experiments conform with Society ethical requirements.