In previous studies, we observed that green or black tea decoction (GTD, BTD) reduced body weight gains and adipose abdominal tissue mass (AATM) in young rats. However, the role of lipids digestibility in this reduction is not yet clear. In the present study, we compared the long-term effect of GTD or BTD consumed ad-libitum on lipid absorption and evaluate its impact on AATM in rats fed high-fat diet (HFD). Thirty-six male Wistar rats were used during an experimental period conducted over 10 weeks. After the adjustment period, the rats were weighed and randomly assigned into 3 groups (n=12 each)with comparable body weights. After, the rats were given the HFD ad libitum with or without tea decoctions as follows: the group 1 received the HFD+ distilled water (CGr), the group 2 received the HFD + GTD (GTGr) and the group 3 received the HFD+ BTD prepared from 50g/L (BTGr). Food intake was recorded throughout the experimental period and quantified by weighing the amount of food spilled and refused. The volume of tea decoction consumed by each rat was measured daily. Fecal matters were individually collected 2 times per week, lyophilized and stored for total polyphenols, total lipids, triglycerides and caffeine analysis. At the end of the experience, the rats were weighed, and then killed by decapitation. Fasting blood was drawn and the plasma was removed for analysis of total polyphenolic compounds, caffeine, total lipids, some metabolic variables and leptin concentration. In addition, liver, perirenal and epididymal white adipose tissues from abdominal cavity were removed, weighed and stored at -20°C until lipid analysis. Values are means ± S.E.M., compared by ANOVA. After 10 weeks treatment, GTD and BTD reduced body weight gains (CGr: 114.8 ± 5.5 vs. GTGr: 86.8 ± 6.4 and BTGr: 67.8 ± 7.8 g, p<0.05) and AATM (CGr: 5.04 ± 0.16 vs. GTGr: 3.13 ± 0.24 and BTGr: 1.97 ± 0.9 g, p<0.05). Additionally, they increased plasma polyphenols (CGr: 31 ± 3.3 vs. GTGr: 101.3 ± 6 and BTGr: 76.6 ± 9.4 µg/mL, p<0.05) and plasma caffeine (CGr: 0.625 ± 0.13 vs. GTGr: 4.1± 0.5 and BTGr: 6.5 ± 0.6 µg/mL, p<0.05). In contrast, GTD and BTD increased lipids (CGr: 213.9 ± 15 vs. GTGr: 301.2 ± 7.6 and BTGr: 351.6 ± 6.5 mg/g, p<0.05) and polyphenols (CGr: 112.5 ± 6.2 vs. GTGr: 644 ± 38.9 and BTGr: 643.1 ± 61.9 µg/g, p<0.05) excretion in fecal matter. Results showed that the reduction of AATM may be ascribed to the modulation of lipids digestibility by tea-polyphenol and tea-caffeine in the gastro-intestinal lumen and adipose tissue organ which involved different mechanisms and physiological pathway including sympathetic nervous system regulation.