Record and analyze electrical activity in organoids, cell cultures and brain slices: BioSignal Processing Unit (BioSPU)-integrated plates

Neuroplasticity in Brain Health and Disease (Newcastle University, UK) (2024) Proc Physiol Soc 57, SA11

Research Symposium: Record and analyze electrical activity in organoids, cell cultures and brain slices: BioSignal Processing Unit (BioSPU)-integrated plates

Sercan Deniz1,

13Brain AG Pfäffikon Switzerland,

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Intelligent plates integrating BioSignal Processing Unit (BioSPU)  provide a tool for recording electrogenic cell activity within the same vessel used for culturing cells and organoids. 

The plates establish direct contact between microchips and biological samples, enabling electrophysiological recording and stimulation at single-cell resolution. Researchers working with neurons, cardiomyocytes, retina or beta-pancreatic cells employ this technology to: characterize disease models, monitor iPSC-derived cultures development and organoid activity, conduct neurotoxicity and neuropharmacology studies or assess the impact of inflammation on cellular electrophysiology. 

BioSPU-integrated plates represent the next-gen technology for neuroscience. 



Where applicable, experiments conform with Society ethical requirements.

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