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Contractility of mouse myometrium is altered by pharmacological modulators of store-operated-Ca2+ entry (SOCE)

B Drumm, C Griffin, G Sergeant, K Thornbury, M Hollywood, M Monawar and R Dunne-Sharkey

Proc Physiol Soc 77 (2026) C27

Potentiated contractility of mouse proximal colon by the Orai1 enhancer IA65 is caused by increasing Ca2+ transient firing in interstitial cells of Cajal

B Drumm, C Griffin, D Thean, G Sergeant, K Sanders, K Thornbury, M Hollywood, R Dunne-Sharkey and S Baker

Proc Physiol Soc 77 (2026) C16

Evaluation of the effects of a positive allosteric modulator of ANO1 channels (PAM_16A) on mouse gastric and colonic rhythmicity

BT Drumm, CS Griffin, GP. Sergeant, H Hashitani, H Hattori, H Takano, KD Thornbury, MA Hollywood, N Butt and N Mullins

Proc Physiol Soc 77 (2026) C15

Store-operated Ca2+ entry (SOCE) via Orai channels is a key source of Ca2+ influx in murine urethral smooth muscle to sustain agonist and nerve evoked contractions

B Drumm, C Griffin, G Sergeant, K Thornbury, M Hollywood and N Gupta

Proc Physiol Soc 77 (2026) C14

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