This satellite symposium, Cellular mechanisms of anti-cancer induced cardiotoxicity, highlighted novel strategies to prevent, or reduce, cardiotoxicity resulting from cancer treatment so as to ensure the best cancer care possible.
Symposium organisers
Organiser: Susan Currie, University of Strathclyde, Glasgow, UK
Co-organiser: Margaret Cunningham, University of Strathclyde, Glasgow, UK
Anthracycline toxicity
Chair: Susan Currie, University of Strathclyde, Glasgow, UK
- 09:40 Detoxifying doxorubicin with semi-rational modifications
- Jacques Neefjes, Leiden University, Netherlands
- 10:25 Cardiotoxicity of anti-cancer therapy: clinical context and translational gaps
- Ninian Lang, University of Glasgow, UK
Cellular mechanisms of anti-cancer drug induced cardiotoxicity
Chair: Margaret Cunningham, University of Strathclyde, Glasgow, UK
- 11:20 MAPK signalling in sunitinib-induced cardiotoxicity
- Helen Maddock, Coventry University, UK
- 12:05 Ryanodine receptors are activated by class I kinase inhibitors
- Niall MacQuaide, University of Glasgow, UK
- 12:30 The crosstalk between cardiac and inflammatory cells: functional role in cardiotoxicity
- Jessica Gambardella, University of Salerno, Italy
Models for studying cardiotoxicity
Chair: Susan Currie, University of Strathclyde, Glasgow, UK
- 14:00 hiPSC-CMs in disease modelling and drug screening: characteristics of repolarisation reserve and Ca2+ dynamics
- Jussi Koivumaki, Tampere University, Finland
- 14:45 Receptor tyrosine kinase inhibitors impact on cardiac stem cells and cardiac function
- Andrew Smith, University of Leeds, UK
Models for studying cardiotoxicity
- 15:35 The vascular protective effect of statins on doxorubicin-induced cardiotoxicity
- Michael Cross, University of Liverpool, UK
- 16:00 Microparticles as biomarkers and mediators of endothelial cell injury in VEGF inhibitor-treated cancer patients
- Karla Neves, University of Glasgow, UK
Travel
For information on travelling to Aberdeen, please see Visit Aberdeen.
Physiology 2019 will be hosted at the Aberdeen Exhibition and Conference Centre, Exhibition Ave, Bridge of Don, Aberdeen AB23 8BL. The AECC is the largest convention centre in northern Scotland, hosting 600 events and welcoming over 300,000 visitors each year.
AECC sits right next to the A90. It’s only a 15-minute taxi ride from Aberdeen railway and bus stations in the city centre.
By Bus
- First Bus services – 1 and 2, Park and Ride X40
- Stagecoach services – 62, 63, 67, 68, 25