• Tuesday 25 June - Wednesday 26 June 2024

Command and Control: Unveiling the Regulation of Smooth Muscle Function

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  • Date

    Tue 25 - Wed 26 Jun 2024

  • Location

    Dundalk Institute of Technology, Ireland

This conference will provide an opportunity for researchers studying the full range of smooth muscle organs (vascular, gastrointestinal, urinary tract, airway, reproductive tract etc) to showcase contemporary research on topics such as smooth muscle electrical signalling, calcium dynamics and external control mechanisms, that will further our understanding of the physiology of life.   

The programme will feature contributions from researchers across the UK, Ireland, and beyond and incorporate a dedicated early career researcher (ECR) teaching session, to give an overview of the main excitation pathways and technologies used to study smooth muscle function.

Dr Bernard Drumm

Dundalk Institute of Technology, Ireland

Dr Harry Pritchard

The University of Manchester, UK

Dr Calum Wilson

University of Strathclyde, Glasgow, UK

Dr Matthew Lee

University of Strathclyde, Glasgow, UK
10:30 SA01 Blood pressure regulation by endothelial cell TMEM16A channels

Professor Jonathan Jaggar, The University of Tennessee, US

11:00 SA02 Interstitial cells, drivers of smooth muscle function

Professor Kenton Sanders, University of Nevada, Reno, US

11:30 C01 Contribution of TMEM16A chloride channels to the complex action potential and contraction in human myometrium during normal and dysfunctional labour

Professor Helena Parkington, Monash University, Clayton, Australia

11:45 C02 Potent vasodilatory effects of clinically-relevant concentrations of niclosamide, an anthelmintic drug and TMEM16A channel modulator, on isolated rodent arteries and capillaries

Rachel Kaye, University of Oxford, UK

13:45 C03 Mutation of phenylalanine residues in LINGO1 and LINGO2 transmembrane domain perturb BK gating and inactivation

Professor Mark Hollywood, Dundalk Institute of Technology, Ireland

14:00 C04 Reduced cerebral blood flow due to damaged vascular smooth muscle cell Ca2+ handling in a mouse model of AD

Katy Walsh, University of Manchester, UK

14:45 SA03 M2 receptors and ionic mechanisms in airway smooth muscle contraction: folklore and dogma

Professor Keith Thornbury, Dundalk Institute of Technology, Ireland

15:15 SA04 Reshaping vascular smooth muscle GPCR signaling in essential hypertension

Dr Maria Teresa Perez-Garcia, Universidad de Valladolid, Spain

15:45 C05 KATP channel-Dependent Electrical Signaling Links Capillary Pericytes to Arteriolar Smooth Muscle in the Brain

Dr Thomas Longden, University of Maryland, Baltimore, US

16:00 C06 Characterization of interstitial cells within the mouse gastroesophageal junction

Emer Ni Bhraonain, University of Nevada, Reno, US

09:30 SA05 The TMEM16A anion channel as a key regulator of microvascular blood flow

Professor Paolo Tammaro, University of Oxford, UK

10:00 SA06 Decoding pleiotropic G protein-coupled receptor activity in human pregnancy and labour

Professor Aylin Hanyaloglu, Imperial College London, UK

11:00 C07 Calcium waves and spatio-temporal mapping reveals myosalpinx excitability and propagation along the murine oviduct

Professor Sean Ward, University of Nevada, Reno, US

11:15 C08 Interaction of Anoctamin-1-encoded Ca2+-activated Cl- and voltage-dependent Kv2.1 channels in mouse pulmonary artery smooth muscle and HEK-293 cells

Dr Normand Leblanc, University of Nevada, Reno, US

11:30 C09 Does microtubule depolymerization affect spontaneous or agonist-induced contraction and relaxation in the myometrium?

Dr Sarah Arrowsmith, Manchester Metropolitan University, UK

11:45 C10 The role of membrane potential in corpus cavernosum smooth muscle contractility

Mitchell Mercer, Dundalk Institute of Technology, Ireland

12:00 C11 Interstitial cell of Cajal-like cells (ICC-LC) exhibit dynamic spontaneous activity but are not functionally innervated in mouse urethra

Neha Gupta, Dundalk Institute of Technology, Ireland

13:15 SA07 Not just an affair of the heart: ERG channels in smooth muscles

Professor Iain Greenwood, St Georges, University of London, UK

13:45 SA08 Unravelling the role of post-junctional M2Rs in ASM contractions and their regulation by β-AR agonists

Dr Tuleen Alkawadri, Dundalk Institute of Technology, Ireland

14:15 C12 Contribution of renal TRPM3 channels to blood flow control and blood pressure regulation

Professor José R Lopez-Lopez, Universidad de Valladolid, Spain

14:30 C13 Secretin Modulate Interstitial Cells of Cajal and Inhibits Small Intestinal Motility

Dr Sal Baker, University of Nevada, Reno, US

15:00 SA09 PIEZO1 force sensor in health, disease and therapeutics

Professor David Beech, University of Leeds, UK

15:30 SA10 Spooky intercellular signaling in the vascular endothelium

Professor John McCarron, University of Strathclyde, Glasgow, UK

Registration

Registration is now open and will close 10 June 2024.

Before registering, please read our event terms and conditions.

PLEASE NOTE that meat will not be provided at lunchtime unless specially requested by contacting the events team. All food will be vegetarian in an effort to reduce the carbon footprint of our conferences.

Membership category  Early registration rate until 24 May 2024 Standard registration rate until 10 June 2024
Undergraduate & Master’s member £130.00 £170.00
Postgraduate member £130.00 £170.00
Full member (concessionary) *  £130.00 £170.00
Full member £195.00 £235.00
Fellow member £195.00 £235.00
Honorary Fellow £195.00 £235.00
Retired member £130.00 £170.00
Non-member £320.00 £420.00
ECR Non-member *  £205.00 £305.00

*please email events@physoc.org for the discount code

Please note, Full Member (concessionary) refers to those who have Full Membership at the reduced rate.

Before registering, please read our event terms and conditions. 

Member registration

In order to register as a member, you first need to log in with username and password. The system will default to the correct fee for your membership category.

Should you have any queries, please email events@physoc.org

Non-member registration

In order to register as a non-member you need to create a guest account.

By joining as a member, you will benefit from reduced registration and other key member benefits including:

  • Free online access to The Society’s three world-class journals
  • Free or discounted registration for Society events
  • Eligibility for Society’s grant schemes

To find out more about membership with The Society, please click here or email membership@physoc.org

Applying for a visa

Do you need a visa to be able to participate in the meeting?

To check whether you need a visa to be able to attend, please click here

For more detailed information, application forms and guidance notes, please visit the Irish Visa website.

It is recommended that you apply for your visa well in advance (at least 12 weeks before the meeting) as applications for Irish visas in certain countries can take longer than expected. Attendees are requested that they book early enough and apply for a visa with sufficient time prior to the conference.

The conference organisers cannot be held responsible if delegates do not receive their visas in time, and the cancellation policy will automatically apply. Every effort will be made to support genuine applications. The conference organisers are happy to provide you with documentation to support your application which will be sent as a PDF attachment. If you require a hard copy to be sent to you, please include your mailing (postal) address. The Physiological Society will only send via regular post.

Documentation to support visa applications will only be provided to those attendees who have registered to attend.

Please complete the webform below, and attach confirmation of your registration, and submitted abstract (if appropriate).

Supporting documentation will be distributed within 10 working days – it is the responsibility of the attendee to allow sufficient time for processing.

Please note that The Society are not involved with and cannot influence consular decisions.

Click here for the visa supporting documents form

 

Abstracts

Abstract submission is now closed. 

All abstracts must be submitted through our abstract submission system provided by Hyperion Live Ltd. You will need to create an account on the system first to submit your abstract. Once logged in you will be able to create a new submission(s) and you can continue to log in and make amends to your abstract(s) until the deadline. If you have any issues or queries when submitting your abstract, please contact events@physoc.org. 

Abstracts can be submitted in one of the following categories: 

  • Original research 
  • Case study 
  • Systematic reviews (including qualitative research) 
  • Technical paper (e.g. methods) 

It is important that the following are included: 

  • Appropriate statistical analysis including n numbers 
  • Appropriate structure including intro, aims/objectives, method, results and conclusions 
  • Compliance with ethical standards 

Please find The Society’s guidelines for creating your abstract here

Early review 

If you require an early review to make visa/travel arrangements, the deadline for submitting your abstract is 8 April 2024. You must notify events@physoc.org if you require an early review. 

Abstracts submitted after 8 April 2024 will be included in the general review. 

Decisions will be issued by 23 April 2024 and will be accept or reject only. No decision will be issued as to the presentation type and status. 

Key Information

Key dates

Registration opens 7 February 2024
Abstract submission opens 27 March 2024
Abstract submission closes 30 April 2024
Early review deadline 8 April 2024
Early bird registration deadline 24 May 2024
Conference Attendance Award deadline 31 May 2024
Registration deadline 10 June 2024
Meeting dates 25-26 June 2024

Venue

The meeting will take place in the Muirhevna Building at Dundalk Institute of Technology (DkIT), Ireland: 

Muirhevna Building
Dundalk Institute of Technology
Marshes Upper
Dundalk
Co. Louth
A91 K584
Republic of Ireland

Travel

By air 
The nearest airport is Dublin Airport.
For your onward journey to DKIT, the Bus Eireann 100x bus leaves Dublin Airport terminal 20 times per day and drops passengers at both DkIT campus and Dundalk town centre.

By train 
Dundalk is served by the mainline train route between Belfast and Dublin, with daily trains. DkIT is a 25 minute walk from Dundalk’s Clarke Train station. Visit the Irish Rail website to plan your journey.

By bus 

There are many buses servicing the DkIT and Dundalk area daily. Visit the Bus Eireann website to plan your journey.

Accommodation

We do not have a specific conference hotel so attendees are able to choose accommodation which meets their needs and budgets. The following accommodation is within a 15 minute walk of the venue:

The Gateway Hotel 

Rosemount B&B

Other accommodation options can be found here.

Support to Attend

The grants below support attendance at our events.

Grants for Carers

We care because you do. We are aware that many of our members have caring responsibilities or need care. We have funds allocated to help you with care costs to facilitate your attendance at meetings.

Find out more

Conference Attendance Award

Up to £375 for the support of member engagement at our own meetings. The deadline for this meeting is 31 May 2024.

Find out more

Partner with Us

Partnering with us provides you with the ideal platform to highlight your brand, products and services to our members and the broader physiology community of researchers and educators.  

In addition, attending our conferences also gives you an invaluable opportunity to network with influential scientists from around the UK, Europe and further afield.  

All external funding is used to support the scientific community by keeping event registration fees at an affordable level and to achieve the charitable aims of The Society.   

Partner Packages

Opportunities range from a standard tabletop exhibition space, to more comprehensive sponsorship packages, including advertising, session sponsorship and speaking slots at the meeting.   

To discuss your requirements in more detail and build a package that suits you, contact us today at events@physoc.org  

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