• Thursday 02 September - Friday 03 September 2021 : Online Symposium

New Roles for Ion Channels and Transporters in Health and Disease

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  • Date

    Thu 02 - Fri 03 Sep 2021

  • Location

    Online

Join us on the afternoons of 2 and 3 September for greater insights into the role of ion channels and transporters in health and disease. Our international panel of speakers will explore key themes including recent developments in epithelial transport physiology, comparative ion transport physiology and dysregulation of ion transport processes in disease. 

There will also be the opportunity to present and discuss your own work as one of six oral communications or as an ePoster during the ePoster sessions. 

Professor Margarida Amaral

University of Lisboa, Portugal

Professor Annarosa Arcangeli

University of Florence, Italy

Dr William Brackenbury

University of York, UK

Professor Robert Fenton

Aarhus University, Denmark

Professor Dr Stefan Gründer

RWTH Aachen University, Germany

Professor David Thwaites

Newcastle University, UK

Supported by The Journal of Physiology

13:00 Using the genome to correct the ion transport defect in cystic fibrosis

Professor Margarida Amaral, University of Lisboa, Portugal

13:30 Potassium versus aldosterone: A battle for control of the distal nephron

Professor Robert Fenton, Aarhus University, Denmark

14:00 OC01 Interleukin-13 increases amiloride-insensitive water resorption in airway epithelia

Dr Hanna Schmidt, Ulm University, Germany

14:15 OC02 The bitter taste receptor agonist denatonium influences mouse tracheal epithelial ion transport

Praveen Kumar, Saarland University, Germany

15:00 Amino acid transport: From human gut to the insect/microbe symbiotic interface

Professor David Thwaites, Newcastle University, UK

15:30 Neuropeptides and DEG/ENaC channels: A relationship from cnidarians to mammals

Professor Dr Stefan Gründer, RWTH Aachen University, Germany

16:00 OC03 Nematode ASICs drive motor behaviour by maintaining intestinal lumen pH and interacting with calcium oscillations

Eva Kaulich, University of Cambridge, UK

Presenters will present a three-minute pitch of their research. Following the pitches, there will be the opportunity for further discussion with the presenters in breakout rooms.
PC01 Activation of tracheal brush cells promotes Trpm5-dependent innate immune responses in Pseudomonas aeruginosa infection
Saskia Evers, Saarland University, Germany
PC02 The cardiotonic steroids digoxin and marinobufagenin modulate tight and gap Junctions through the Na+, K+ - ATPase
Alejandro Ogazon Del Toro, CINVESTAV, Mexico
PC03 Differential expression of store operated calcium entry complex proteins in human skin and sweat gland cell lines
Carmela Errico, Glasgow Caledonian University, UK
PC04 Modulation of impaired uterine contractility by Transient Receptor Potential cation TRPV4 and TRPC4 channels
Dr Olesia Moroz, Taras Shevchenko National University of Kyiv, Ukraine
PC05 AMP-activated protein kinase promotes dephosphorylation of Na+, K+-ATPase at Tyr10 of the α1-subunit in kidney and skeletal muscle cells
Metka Petrič, University of Ljubljana, Slovenia
PC06 The inhibitory action of single-walled carbon nanotubes on TRPC4-mediated muscarinic cation current in mouse ileal smooth muscle cells
Dr Mariia Melnyk, National Academy of Sciences of Ukraine
PC07 Prostaglandin E2 increases iIntercelular communication through gap junction channels
Alejandro Ogazon Del Toro, CINVESTAV, Mexico
PC08 Possible involvement of ionotropic receptor gene modulations in mesio-temporal lobe epilepsy
Arif Kamil Salihoglu, Karadeniz Technical University, Turkey
PC09 Potassium-selective stretch-activated ion channels are present in human atrial fibroblasts: Exploring a possible role in mechano-induced fibrosis
Elisa Darkow, University of Freiburg, Germany
PC10 Decreased intrinsic excitability potentiation of CA1 pyramidal neurons induced by neonatal blockade of NMDA receptors
Ernesto Griego, CINVESTAV, Mexico
PC12 Common molecular mechanisms among prestin (SLC26A5) and other members of the SLC26 family
Dominik Lenz, Philipps University of Marburg, Germany
PC13 Targeting G protein-gated inwardly rectifying potassium (GIRK) channels in the central nervous system
Danko Jeremic, Universidad de Castilla-La Mancha, Spain
PC14 Epilepsy-causing KCNT1 variants increase KNa1.1 channel activity by disrupting the activation gate, which is partially restored by wild-type subunit coexpression
Bethan Cole, University of Leeds, UK
PC11 Novel CACNA1I/Cav3.3 calcium channel variants associated with Hemiplegic Migraine
Dr Rocio Finol-Urdaneta, University of Wollongong, Australia
13:00 The role of potassium channels in tumours of the GI tract 

Professor Annarosa Arcangeli, University of Florence, Italy

13:30 Sodium channels and the ionic microenvironment of breast tumours 

Dr William Brackenbury, University of York, UK

14:00 OC04 Effects of the skeletal Ryanodine Receptor Type 1 mutation on uterine artery vascular smooth muscle function and fetal growth in pregnant RyR1Y522S/+ mice

Arti Mistry, King’s College London, UK

14:15 OC05 Characterisation of T1019PfsX38 hERG mutation reveals changes in channel gating dynamics

Dr Majid K Al Salmani, University of Nizwa, Oman

14:30 OC06 Cholinergic control of ATP-mediated interkleukin-1β release in monocytes involves endothelial NO synthase

Dr Katrin Richter, University of Giessen, Germany

Presenters will present a three-minute pitch of their research. Following the pitches, there will be the opportunity for further discussion with the presenters in breakout rooms.
P15 Functionally enhanced but not codon optimized CFTR cDNAs increased Cl- transport and airway-surface-liquid height when expressed in Cystic Fibrosis airway epithelial cells
Professor Deborah Baines, St Georges University of London, UK
PC16 Vitamin D receptor activation exerts anti-secretory actions in colonic epithelial cells
Caitriona Curley, RCSI Dublin, Ireland
PC17 Aquaporin 3 limits transepithelial fluid resorption upon exposure to hyperosmotic solutions in airway epithelia
Alexander Sauter, Ulm University, Germany
PC18 Species dependent differences in cystic fibrosis transmembrane conductance regulator (CFTR) channel gating and response to the potentiator ivacaftor
Demi Ng, University of Bristol, UK
PC19 Longitudinal micro-computed tomography and lung function analysis provide insight into emphysema pathogenesis in βENaC-tg mice
Sean Gettings, Newcastle University, UK
PC20 Development of in vitro transcribed mRNA therapeutics for cystic fibrosis
Dr Ruhina Maeshima, University College London, UK
PC21 Aquaporin-3 silencing impairs barrier function of airway epithelia
Magdalena Fuchsberger, Ulm University, Germany
PC22 Regulation of the cystic fibrosis transmembrane conductance regulator (CFTR) by the nuclear bile acid receptor, farnesoid X receptor
Jessica Smyth, RCSI Dublin, Ireland
PC23 Influence of lauric acid on the relaxation of corpus cavernosum in streptozotocin induced diabetic male Wistar rats
Makinde Olubiyi, Kogi State University, Nigeria
PC24 The acidic breast cancer microenvironment increases Na+ entry into cancer cells through voltage gated sodium channels
Theresa Leslie, University of York, UK
PC25 Upregulated antimicrobial peptide expression protects slc26a3-/- mice from gut inflammation despite dysbiosis
Archana Kini, Hannover Medical School, Germany
PC26 Differential roles of Beta-Cell IP3R and RyR ER Ca2+ channels in tunicamycin-induced disruption of Beta-Cell Ca2+ homeostasis
Dr Irina Zhang, University of Michigan, USA
PC27 Screening novel inhibitors of the neutral amino acid transporter B0AT1 (SLC6A19), a potential target to treat metabolic diseases
Aditya Yadav, The Australian National University, Canberra, Australia
PC28 Store-operated Ca2+ entry in uterine endometrial cancer
Dr John Mackrill, University College Cork, Ireland
PC29 Effects of obesity and diabesity on calcium signaling in ventricular myocytes from the Zucker rat
Ahmed Sultan, United Arab Emirates University, UAE
PC30 Ablation of Na+/H+ exchanger-3 prevents tissue iron loading in the Hfe mouse model of hereditary hemochromatosis
Dr Corbin R Azucenas, University of Cincinnati, Ohio, USA

Registration

Registration is now open and will close on 26 August.

Before registering, please read our event terms and conditions.

Registration is free for all members of The Society. There is a £30.00 fee for non-members.

In order to register as a member, you first need to log in with your username and password.

In order to register as a non-member, you first need to create a guest account.

By joining as a member, you will benefit from reduced registration and other key member benefits including:

  • Free online access to The Society’s three world-class journals
  • Free or discounted registration for Society events
  • Eligibility for The Society’s grant schemes

To find out more about membership with The Society, please click here or email membership@physoc.org.

Abstract submission

View the abstract book

Abstract submission is now closed.

Abstracts can be submitted in one of the following categories:  

  • Original research  
  • Case study
  • Systematic reviews (including qualitative research)  
  • Technical paper (e.g. methods)  

It is important that the following are included:  

  • Appropriate statistical analysis including n numbers  
  • Appropriate structure including intro, aims/objectives, method, results and conclusions  
  • Compliance with ethical standards  

Please find The Society’s guidelines for creating your abstract here. 

Submitting your abstract

The Society’s abstract management platform is Firebird Conferences Systems.    

You will need to log in or sign up for an account to submit an abstract on the Firebird submission site. If you have submitted an abstract on the Firebird submission site before, such as for Future Physiology 2020 or 2021 or Physiology 2021, you can log in using these details. 

More information about both oral and ePoster presentations will be sent to authors of selected abstracts. 

Key info

Registration opens 18 May 2021 
Abstract submission opens  1 June 2021 
Abstract submission closes  30 June 2021 
Abstract decisions released  23 July 2021 (subject to change) 
Registration deadline  26 August 2021 
Meeting dates  2 – 3 September 2021 
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