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  • Autumn 2006 - Issue Number 64
  • Autumn 2006 - Issue Number 64

Below are the feature articles from Physiology News Issue 64, Autumn 2006.

To read the full articles please download the issue.

  • Features

Vitamin D and disease prevention

Vitamin D, produced by sunlight exposure of the skin, is essential in mineral metabolism and skeletal health. The high prevalence of vitamin D insufficiency and its association with increased risk for osteoporosis, diabetes, tuberculosis, autoimmune diseases, and cancer have prompted the re-evaluation of daily requirements
  • Features

Variability of human vagal baroreflex responses

In ‘steady-state’ resting humans, baroreflex gain fluctuates hugely and rhythmically at very low frequencies
  • Features

Neuronal lactate metabolism

The first piece of the jigsaw falls into place
  • Features

Muscle damage and exercise: does the brain contribute to muscle weakness?

Some forms of exercise lengthen contracting muscles. This damages the myofibrils when we are not accustomed to the exercise, and full recovery takes some days. Recent studies by Simon Gandevia and colleagues have looked not only at the peripheral changes in the muscle but at the changes in the central nervous system. Voluntary activation of the muscle is impaired after eccentric exercise and contributes to muscle weakness. This impairment depends on the length of the muscle
  • Features

Autoregulation of neuronal activity by presynaptic GABA ARs

Presynaptic GABAA receptors have recently been identified in several cell types. Alain Marty and Sheyla Mejia-Gervacio present evidence showing that these receptors are able to shape neuronal firing patterns and discuss the role of this regulatory process for the maturation of synaptic networks in the cerebellum
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