Are Young Motoneurones Worked to Death? – Maggie Lowrie, Gerta Vrbova & Linda Greensmith (p.16)

It has been known for many years that developing motoneurones depend upon continuous interaction with their target muscle for survival. This seems to be the main factor which distinguishes winners from losers during the embryonic period of programmed cell death, and also explains the vulnerability of early postnatal motoneurones after nerve injury.