Mike’s main research focus is to investigate the regulation and impact of changes in ion transport on the heart in health and disease such as cardiac hypertrophy, heart failure, ischaemia / reperfusion, arrhythmias and hypertension. More recently, a programme of work aimed at understanding the influence of cardiac autonomic input on electrophysiology has led to the concept of ‘autonomic conflict’ as a contributor to lethal arrhythmias and sudden cardiac death.