Scientific Programme

Friday 10 April 2015

9.00 Welcome and Introduction
Ken O'Halloran (Meetings Secretary, The Physiological Society)

9.15 Plenary Lecture
Healthy cognitive ageing
Ian Deary (University of Edinburgh, UK)

10.00 Coffee

10.30 Ageing, exercise and brain health
Organiser: Marc J Poulin (University of Calgary, Canada)

12.30 Lunch and Poster Viewing

13.30 From TOP to TOE: What falls reveal about physiological ageing and degeneration
Organiser: Simon Gandevia (Neuroscience Research Australia, Australia)

15.35 Coffee

16.00 Limitations of skeletal muscle oxygen supply in ageing
Organiser: Ylva Hellsten (University of Copenhagen, Denmark)

18.00 Drinks reception

19.00 End of day one


Saturday 11 April 2015

9.00 Ageing, physical activity and neurodegeneration
Organiser: Paul Greenhaff (University of Nottingham, UK)

11.00 Coffee

11.30 Membrane/lipid rafts: Age-associated changes in membrane biology and function
Organiser: Brian P Head (VASDHS/UCSD, USA)

13.35 Lunch and Poster Viewing

14.30 Mechanisms of cerebellar ataxias and neurodegeneration
Organisers: Mandy Jackson (University of Edinburgh, UK) & Ian D Forsythe (University of Leicester, UK)

16.35 Poster Session

18.30 End of Meeting

19.00 Society Dinner



Programme with full speaker details

Friday 10 April 2015

9.00 Welcome and Introduction
Ken O'Halloran (Meetings Secretary, The Physiological Society)

9.15 Plenary Lecture
Healthy cognitive ageing
Ian Deary (University of Edinburgh, UK)

10.00 - 10.30
Coffee

10.30 – 12.30
Ageing, exercise and brain health
Organiser: Marc J Poulin (University of Calgary, Canada)

10.30 - 11.00 Dale Corbett (University of Ottawa, Canada)
Ageing, exercise and recovery of motor and cognitive function following stroke

11.00 - 11.30 Gail A Eskes (Dalhousie University, Canada)
Enhancing cognition in aging and vascular disease

11.30 - 12.00 Kirk Erickson (University of Pittsburgh, USA)
Effects of exercise on the hippocampus and memory in older adults

12.00 - 12.15 Philippa Jackson (Northumbria University, UK)
Role of nutritional supplementation on brain health in older adults

12.15 - 12.30 Vincent Pialoux (Universite Claude Bernard Lyon 1, France)
Cardiorespiratory fitness, exercise training, cerebrovascular function and oxidative stress in older adults / animals

12.30 – 13.30
Lunch and Poster Viewing

13.30 – 15.35
From TOP to TOE: What falls reveal about physiological ageing and degeneration
Organiser: Simon Gandevia (Neuroscience Research Australia, Australia)

13.30 - 13.55 Stephen Lord (Neuroscience Research Australia, Australia)
Pathophysiology of falls, balance and falls prevention

13.55 - 14.20 Mark Rogers (University of Maryland, USA)
Stepping for stability: A physiological protection against falls in ageing

14.20 - 14.45 Mirjam Pijnappels (Vrije Universiteit Amsterdam, The Netherlands)
Age-related changes in balance control during walking

14.45 - 15.10 Kim Delbaere (Neuroscience Research Australia, Australia)
Brain imaging and the neuropsychology of risk factors for falls

15.10 - 15.35 Arthur Kramer (University of Illinois, USA)
Walking towards a healthier brain & mind

15.35 – 16.00
Coffee

16.00 – 18.00
Limitations of skeletal muscle oxygen supply in ageing
Organiser: Ylva Hellsten (University of Copenhagen, Denmark)

16.00 - 16.30 Frank Dinenno (Colorado State University, USA)
Skeletal muscle blood flow supply in aged individuals

16.30 - 17.00 Dick Thijssen (Liverpool John Moores University, UK and Radboud University, The Netherlands)
Arterial structure and vascular function in ageing

17.00 - 17.30 Judy Mueller Delp (Florida State University College of Medicine, USA)
Skeletal muscle microvascular function in ageing

17.30 - 17.45 Michael Nyberg (University of Copenhagen, Denmark)
Reduced skeletal muscle blood flow and oxygen uptake in ageing: is it all an effect of sand through the hourglass?

17.45 - 18.00 Birgitte Hoier (University of Copenhagen, Denmark)
Angiogenic potential and capillary growth in response to training in ageing

18.00 – 18.30
Drinks Reception

Saturday 11 April 2015

09.00 – 11.00
Ageing, physical activity and neurodegeneration
Organiser: Paul Greenhaff (University of Nottingham, UK)

09.00 - 09.30 Simon Gandevia (Neuroscience Research Australia, Australia)
The brain-muscle axis in human ageing

09.30 - 10.00 Karolina Rygiel (Newcastle University, UK)
Mitochondrial DNA deletions and neuromuscular degeneration: Implications to human ageing

10.00 - 10.15 Aphrodite Vasilaki (University of Liverpool, UK)
Age-related changes in the interactions between nerve and muscle

10.15 - 10.45 Lutz Jäncke (Zurich University, Switzerland)
The ageing but nevertheless plastic brain

10.45 - 11.00 James Fisher (University of Birmingham, UK)
The impact of age on cerebral perfusion, oxygenation and metabolism during exercise in humans

11.00 – 11.30
Coffee


11.30 – 13.35
Membrane/lipid rafts: Age-associated changes in membrane biology and function
Organiser: Brian P Head (VASDHS/UCSD, USA)

11.30 - 11.55 Fiona Murray (University of Aberdeen, UK)
Targeting cAMP in Chronic Lymphocytic leukaemia

11.55 - 12.20 Brian P Head (VASDHS/UCSD, USA)
MLR, Cav-1, and neurorepair

12.20 - 12.45 Sameh S Ali (Zewail City of Science and Technology, Egypt)
Monitoring reactive oxygen species in synaptosomal lipid rafts

12.45 - 13.10 Hemal H Patel (VASDHS/UCSD, USA)
Non-canonical roles for caveolin in cell growth and survival

13.10 - 13.35 Dermot Cooper (University of Cambridge, UK)
Adenylyl cyclase-centred signalling microdomains

13.35 – 14.30
Lunch and Poster Viewing

14.30 – 16.35
Mechanisms of cerebellar ataxias and neurodegeneration
Organisers: Mandy Jackson (University of Edinburgh, UK) & Ian D Forsythe (University of Leicester, UK)

14.30 - 14.55 Mandy Jackson (University of Edinburgh, UK)
Glutamate transporters and ataxia: Zonal susceptibility of Purkinje cells to loss of EAAT4 and GLAST

14.55 - 15.20 Thomas Otis (Geffen School of Medicine at UCLA, USA)
Cellular and circuit mechanisms underlying spinocerebellar ataxia type 2

15.20 - 15.45 Leonard Kaczmarek (University of Yale, USA)
The Kv3.3 potassium channel triggers Arp2/3-dependent actin nucleation to regulate inactivation and cell survival

15.45 - 16.10 Gary Stephens (University of Reading, UK)
Cannabinoid signalling and cerebellar ataxia

16.10 - 16.35 Ruth Empson (University of Otago, New Zealand)
Moderation of enhanced metabotropic glutamate receptor (mGluR1) mediated synaptic signalling restores motor learning in a mouse model of human spino-cerebellar ataxia type 1, SCA1

16.35 – 18.30
Posters

19.00
Society Dinner

Summary

• Ageing, exercise and brain health Organiser: Marc J Poulin (University of Calgary, Canada)
• From TOP to TOE: What falls reveal about physiological ageing and degeneration Organiser: Simon Gandevia (Neuroscience Research Australia, Australia)
• Limitations of skeletal muscle oxygen supply in ageing Organiser: Ylva Hellsten (University of Copenhagen, Denmark)
• Ageing, physical activity and neurodegeneration Organiser: Paul Greenhaff (University of Nottingham, UK)
• Membrane/lipid rafts: Age-associated changes in membrane biology and function Organiser: Brian P Head (VASDHS/UCSD, USA)
• Mechanisms of cerebellar ataxias and neurodegeneration Organisers: Mandy Jackson (University of Edinburgh, UK) & Ian D Forsythe (University of Leicester, UK)