Proceedings Abstracts of The Physiological Society

Cellular Neurophysiology

1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine differentially dissipates mitochondrial membrane potentials in mesencencephalic, striatal and cortical astrocytes

S. Senok1, A. Stadlin2

Proc Physiol Soc 27 (2012)

Action potential propagation in myelinated axons of central mammalian neurons relies on calcium entry at nodes of Ranvier

J. Gründemann1, M. Häusser1, B. Clark1

Proc Physiol Soc 27 (2012)

Facebook for neurons? Helping isolated neurons make appropriate connections

G. W. Arbuthnott1, W. A. Staines2, F. Randall1, C. Vickers1, S. C. Schock2, M. Garcia Munoz1

Proc Physiol Soc 27 (2012)

Modulation of neuromuscular synaptic degeneration by activity in WldS mutant mice

R. Brown1, D. Thomson1, R. R. Ribchester1

Proc Physiol Soc 27 (2012)

Nitric oxide (NO) potentiates an SK-mediated afterhyperpolarising potential (AHP) in mouse MNTB neurons

A. J. Tozer1,2, J. R. Steinert2, I. D. Forsythe1

Proc Physiol Soc 27 (2012)

Nitric oxide induces a hyperpolarizing shift in the half-activation voltage of HCN1, but not HCN2 dominated currents in mouse brainstem neurons

C. Kopp-Scheinpflug1, I. D. Forsythe2

Proc Physiol Soc 27 (2012)

BACE1: a novel regulator of neuronal glucose metabolism

J. Findlay1, L. Hamilton1, P. Meakin1, C. Beall1, M. Ashford1

Proc Physiol Soc 27 (2012)

Characterisation of cells in the postnatal neurogenic niche surrounding the central canal of the mammalian spinal cord

L. Corns1, J. Burgess1, J. Deuchars1, S. A. Deuchars1

Proc Physiol Soc 27 (2012)

Synaptic responses in the inferior olive to projections from the neocortex

D. L. Garden1, M. F. Nolan1

Proc Physiol Soc 27 (2012)

Release parameters at single site synapses between rat cerebellar interneurons investigated in vitro with laser photolysis of Ca-DM-nitrophen

F. F. Trigo3, T. Sakaba2, D. Ogden1, A. Marty4

Proc Physiol Soc 27 (2012)

Evidence that endogenous TGF-??2 is released by activity as a retrograde modulator of synaptic transmission

T. Kai Chun1, I. S. McLennan2, G. S. Bewick1

Proc Physiol Soc 27 (2012)

NMDA receptor stimulation triggers PFKFB3 stabilization causing pentose-phosphate pathway to glycolysis shift in primary cortical neurons.

P. Rodriguez1, E. Fernandez1, A. Almeida1,2, J. Bolaños1

Proc Physiol Soc 27 (2012)

Preproglucagon neurons innervate spinal autonomic neurons

R. Manton1, I. J. Llewellyn-Smith2, F. Reimann3, F. M. Gribble3, S. Trapp1

Proc Physiol Soc 27 (2012)

Forced swim stress is as an effective physical stress in reinstating morphine-induced place preference in rats

G. Attarzadeh Yazdi1, A. Haghparast2, S. Karimi2, S. Yazdi-Ravandi2

Proc Physiol Soc 27 (2012)

A general mathematical model of transduction events in mechano-sensory stretch receptors

T. Suslak1,3, D. Armstrong3,1, A. P. Jarman2

Proc Physiol Soc 27 (2012)

The AMP-Activated Protein Kinase (AMPK)-Uncoupling Protein 2 (UCP2) pathways controls glucose sensing and whole body glucose counterregulation in mouse

C. Beall1, D. L. Hamilton1, L. Logie1, F. Ashford1, M. P. Soutar1, J. Gallagher1, E. Haythorne1, X. Fan2, S. Diano3, M. L. Ashford1, R. J. McCrimmon1,2

Proc Physiol Soc 27 (2012)

Pharmacological profile of non-canonical mGluR regulating mechanosensory nerve terminal firing

S. Watson1, C. Zanato1, S. Dall'Angello1, R. W. Banks2, I. Greig1, M. Zanda1, G. S. Bewick1

Proc Physiol Soc 27 (2012)

Low open probability receptor activation reveals a mechanism for the partial agonist action of sarcosine at rat GluN1/GluN2B NMDA receptors

P. E. Chen1, A. J. Gibb2

Proc Physiol Soc 27 (2012)

Exploring the mechanism of action of a novel remyelinating therapeutic

E. A. Keogh1, R. Murphy1, M. Pickering1, K. J. Murphy1

Proc Physiol Soc 27 (2012)

The glycogen contribution to lactate release from adult mouse optic nerve is dependent upon tissue energy demand

A. M. Brown1, R. Evans1

Proc Physiol Soc 27 (2012)

A confocal study of the coexistence of neuronal nitric oxide synthase and tyrosine hydroxylase in the rat nigrostriatal pathway

M. Mitkovski5, F. E. Padovan-Neto1, R. Raisman-Vozari2,3, L. Ginestet3,4, E. Del Bel1

Proc Physiol Soc 27 (2012)

Model of organophosphorus toxicity in mice

K. N. Dissanayake1, R. R. Ribchester1, M. Eddleston1

Proc Physiol Soc 27 (2012)

Short-term synaptic plasticity in the sensory thalamus controlled by sleep state-related neuromodulators

Y. Yang1, C. Hu1

Proc Physiol Soc 27 (2012)

The acetylcholine receptor current of neonatal mouse inner hair cells

M. G. Evans1, H. J. Kennedy2

Proc Physiol Soc 27 (2012)

Acute metabotropic glutamate receptor-dependent synaptic plasticity in a mouse model of fragile-X syndrome

S. Barnes1, T. O'Leary1, P. C. Kind1, D. J. Wyllie1

Proc Physiol Soc 27 (2012)

GPCR constitute the local Ca2+ signaling which modulate the activation of Ca2+ activated Cl- channel

X. Jin1

Proc Physiol Soc 27 (2012)

Role of the neuronal glutamate transporter, EAAT4, in cerebellar Purkinje neuron intrinsic activity

E. M. Perkins1, T. Van Slageren1, Y. L. Clarkson1, K. Tanaka2, M. Jackson1

Proc Physiol Soc 27 (2012)

Dopamine-induced regulation and de-regulation of catabolism of cyclic ADP-ribose, an intrinsic mTOR signal inhibitor, during development in the rodent striatum

C. Higashida-Tsuji1,2, M. Islam1, J. Duo1, T. Tsuji1,2, H. Higashida1

Proc Physiol Soc 27 (2012)

Localised calcium signalling at the inner hair cell ribbon synapse of the adult mouse

A. M. Garcia de Diego1, D. E. Fordham1, J. Ashmore1,2

Proc Physiol Soc 27 (2012)

Expression profile of large conductance calcium-voltage operated potassium channels in an animal obesity model

T. Scullion1, H. Widmer1, S. Dolan1

Proc Physiol Soc 27 (2012)

Co-existence of theta-nested gamma oscillations and grid firing fields in an attractor network model

L. Solanka1, M. van Rossum2, M. Nolan3

Proc Physiol Soc 27 (2012)

Commissural control of frequency selectivity in the inferior colliculi

L. Orton1, A. Rees1

Proc Physiol Soc 27 (2012)

Dynamins and myosin-II may regulate the switching between the distinct modes of exocytosis in control and diabetic nerve terminals in a Ca2+ dependent manner

D. A. Bhuva1, A. C. Ashton1

Proc Physiol Soc 27 (2012)

TGF-??2 acutely reverses some of the deficits in neuromuscular transmission in a mouse model of motor neurone disease

J. Reid1, G. B. Miles2, G. S. Bewick1

Proc Physiol Soc 27 (2012)

Electrical stimulation applied to the amygdala facilitates secretion of endogenous opiods in the periaqueductal gray

T. Nakamura1, M. Tomida1, H. Ando1, N. Asanuma1, T. Takamata2, E. Kondo3

Proc Physiol Soc 27 (2012)

Astrocytes use lactate to stimulate neuronal noradrenaline release in the locus coeruleus

S. Lane1, S. Kasparov1, A. G. Teschemacher1

Proc Physiol Soc 27 (2012)

Effect of Neuronal Nitric Oxide Synthase inhibitor on the expression of cyclooxygenase-2 and glial cells in hemi-parkinsonian rats with levodopa-induced dyskinesias

R. Cavalcanti-Kwiatkoski1,2, M. Bortolanza2, R. Raisman-Vozari3, E. A. Del Bel2

Proc Physiol Soc 27 (2012)

Immunohistochemical evidence for neuronal and glial expression of the inward rectifying potassium channel subtype Kir7.1 in the mouse brain

M. Papanikolaou1, V. Bay1, A. Lewis1, A. M. Butt1

Proc Physiol Soc 27 (2012)

Hypothalamic glucosensing neurons display defective electrical response to low glucose following antecedent ATP-sensitive K+ channel activation

E. A. Haythorne1, C. Beall1, D. Hamilton1, M. L. Ashford1, R. J. McCrimmon1

Proc Physiol Soc 27 (2012)

Gene expression signature of Gamma hydroxybutyric acid (GHB) exposure in Human monocytic leukaemia THP-1 cells

A. Abdullah1, E. Ellis1

Proc Physiol Soc 26 (2012)

A novel viral tool to study ATP-mediated signalling in the brain

M. Figueiredo1, V. Kasimov2, N. Marina2, A. V. Gourine2, A. G. Teschemacher1, S. Kasparov1

Proc Physiol Soc 23 (2011)

VEGF-A165b is neuroprotective in in vitro models of diabetic and chemotherapy-induced sensory neuropathy and prevents ipsilateral DRG ATF-3 upregulation after nerve injury in vivo

N. Beazley-Long1, R. P. Hulse2, S. J. Harper1, D. O. Bates1, L. F. Donaldson2

Proc Physiol Soc 23 (2011)

Evidence of a role for astrocyte purinergic signalling in regulation of extracellular potassium and action potential propagation in central nervous system white matter

V. Bay1, P. Hurst1, A. Butt1

Proc Physiol Soc 23 (2011)

Human embryonic stem cell derived functional astrocytes are neuroprotective through glutathione dependent and independent mechanisms

K. Gupta1,2, R. Patani1, P. Baxter2, A. Serio2, D. Story2, J. D. Pickard1, R. A. Pedersen1, G. E. Hardingham2, S. Chandran2

Proc Physiol Soc 23 (2011)

Are astroglial Gq-protein coupled receptors functionally relevant?

S. Lane1, N. Marina2, A. V. Gourine2, A. G. Teschemacher1, S. Kasparov1

Proc Physiol Soc 23 (2011)

Differential control of striatal inhibition by histamine

T. Ellender1, I. Huerta-Ocampo1, M. Capogna1, P. Bolam1,2

Proc Physiol Soc 23 (2011)

Investigating glycine-activated currents in rat substantia nigra neurones

J. M. Hallett1, S. Jones1

Proc Physiol Soc 23 (2011)

Electrophysiological deficits at GABAergic synapses on Purkinje cells of the dystrophin-deficient mdx mouse: possible implications for Duchenne Muscular Dystrophy

S. I. Head1, J. W. Morley2, S. L. Kueh2, J. Dempster3

Proc Physiol Soc 23 (2011)

Gene expression in glycyl tRNA synthetase (GARS) related neurodegeneration

J. Li1, C. Coxon1, S. Lee1, A. Goyenvalle1, G. Weir1, K. Talbot1, K. Davies1, Z. Cader1

Proc Physiol Soc 23 (2011)

Development of physiologically correct neural inputs for an in vitro model of skeletal muscle.

A. Smith1,3, V. Mudera2, L. Greensmith1, M. Lewis3

Proc Physiol Soc 23 (2011)