Proceedings Abstracts of The Physiological Society

Respiratory Physiology

P2X4 null mice have a salt-sensitive blood pressure and impaired ENaC-mediated sodium reabsorption

E. Craigie1, D. G. Shirley1, S. S. Wildman2,1, R. J. Unwin1

Proc Physiol Soc 27 (2012)

Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells

J. M. Street1, W. Birkhoff1, R. I. Menzies1, D. J. Webb1, M. A. Bailey1, J. W. Dear1

Proc Physiol Soc 27 (2012)

Zaprinast can correct phosphate induced impaired relaxation in rat resistance vessels

K. Stevens1, E. C. Beattie1, G. Smith1, S. Kettlewell1, C. Delles1, R. K. Patel1, A. G. Jardine1

Proc Physiol Soc 27 (2012)

The effects of Syzygium aromaticum-derived oleanolic acid on kidney function of male Sprague-Dawley rats and on kidney cell lines

H. Madlala1, B. Masola2, M. Singh2, C. T. Musabayane1

Proc Physiol Soc 27 (2012)

Iron-induced switching of a receptor mediated transferrin uptake in epithelial cells

M. Haley1, M. Lowe1, C. P. Smith1

Proc Physiol Soc 27 (2012)

Fluorescence imaging reveals differences in mitochondrial function along the collecting duct

H. R. Courtneidge1, C. Crawford2, A. M. Hall1, C. M. Peppiatt-Wildman2

Proc Physiol Soc 27 (2012)

Dissociation of structure from function in the distal renal tubule of mice lacking 11??-hydroxysteroid dehydrogenase type 2

R. W. Hunter1, L. Mullins1, M. A. Bailey1, J. J. Mullins1

Proc Physiol Soc 27 (2012)

Evaluation of salt appetite in brain specific 11?? hydroxysteroid dehydrogenase type 2 knockout mice (11??HSD2-/-)

L. Evans1, J. Mullins1, M. Holmes1, M. Bailey1

Proc Physiol Soc 27 (2012)

An acute duodenal phosphate load does not downregulate renal sodium phosphate co-transporters

G. Lee1, J. Marks2, E. S. Debnam2, R. J. Unwin1,2

Proc Physiol Soc 27 (2012)

Functional characterization of ClC-Kb mutations found in patients with Bartter syndrome

M. Keck1, O. Andrini1, S. L'Hoste1, T. Grand1, R. Vargas-Poussou2, A. Blanchard3, S. Lourdel1, J. Teulon1

Proc Physiol Soc 27 (2012)

An investigation of the effects of Caffeic acid against oxidative and endoplasmic reticulum stress in renal proximal tubular cells

L. Mealey1,2, A. S. Pannala2, P. K. Chatterjee2

Proc Physiol Soc 27 (2012)

An investigation of the effects of fetuin-A on paraquat-induced oxidative injury in renal proximal tubular epithelial cells

L. C. Holland1,2, P. K. Chatterjee2

Proc Physiol Soc 27 (2012)

A comparison of the effects of minocycline and 5-aminoisoquinolinone on paraquat-induced oxidant injury in renal epithelial cells

D. Katarey1,2, P. K. Chatterjee2

Proc Physiol Soc 27 (2012)

Tyramine-evoked release of endogenous noradrenaline constricts in situ vasa recta diameter via its action at contractile pericytes

C. Crawford1, T. M. Kennedy-Lydon1, J. Munday1, S. S. Wildman2, C. M. Peppiatt-Wildman1

Proc Physiol Soc 27 (2012)

PGE2 modulation of in situ vasa recta diameter is mediated by pericytes: mechanism for NSAID induced nephrotoxicity

T. Kennedy-Lydon1, C. Crawford1, S. SP Wildman2, C. M. Peppiatt-Wildman1

Proc Physiol Soc 27 (2012)

Identification of Anoctamine-1, Ca2+ activated chloride channel in porcine urinary bladder and characterization of its functional role using niflumic acid

D. A. Bijos1,2, M. J. Drake1,2, B. Vahabi1,3

Proc Physiol Soc 27 (2012)

The ergogenic impact of sustained high-dose short acting β2-agonist use during a six week training programme in healthy individuals

J. Molphy1, J. Dickinson1, N. Chester1, M. Loosemore2, G. Whyte1

Proc Physiol Soc 26 (2012)

Chronic intermittent hypoxia does not increase lipid peroxidation in rat diaphragm

H. B. Chow1, R. Williams3, C. M. Shortt1, F. McDonald1, A. Bradford2, K. D. O'Halloran3

Proc Physiol Soc 26 (2012)

Relationship between ventilatory function and age in master athletes and a sedentary reference population

H. Degens1,2, T. M. Maden-Wilkinson1, A. Ireland1, M. T. Korhonen3, H. Suominen3, A. Heinonen3, Z. Radak4, J. S. McPhee1, J. Rittweger2,1

Proc Physiol Soc 26 (2012)

Rapid component of oxygen uptake kinetics is associated to rowing performance in competitive young rowers

C. F. Henríquez Olguín1, M. Tuesta Roa2, D. Morales Broerse2, H. Zepeda Ruiz3, E. Báez San Martín1

Proc Physiol Soc 26 (2012)

Mechanisms of O2 sensing and Ca2+ homeostasis during hypoxic pulmonary vasoconstriction in pulmonary arteries from rats

M. J. Connolly1, J. Prieto-Lloret1, J. P. Ward1, P. I. Aaronson1

Proc Physiol Soc 25 (2011)

Mirror-like SeSAME/EAST renal phenotype in mice lacking the pH-sensitive Kir5.1 (Kcnj16) K+ channel subunit

M. Paulais1, M. Keck1, S. Lourdel1, S. J. Tucker2, J. Teulon1

Proc Physiol Soc 24 (2011)

Relationship between thirst perception and plasma arginine vasopressin concentration in man

L. F. Obika1, E. Amabebe2, F. K. Idu3

Proc Physiol Soc 24 (2011)

In vivo evidence for protease-induced activation of the epithelial sodium channel ENaC in rat collecting duct

G. Jacquillet1, R. J. Unwin1, H. Chichger1, D. G. Shirley1

Proc Physiol Soc 24 (2011)

P2X4 receptors and the epithelial sodium channel in mouse collecting ducts in vivo

E. Craigie1, R. J. Unwin1, S. S. Wildman2, D. G. Shirley1

Proc Physiol Soc 24 (2011)

Acetylsalicylic acid impairs early renal development in cultured embryonic metanephros through a COX-independent mechanism

A. S. Carvalho1, S. J. Welham1, M. J. Elmes1

Proc Physiol Soc 23 (2011)

17β-Estradiol increases amiloride-sensitive Na+ current and PKCδ activity in renal collecting duct M1 cells

M. Y. Yusef Robles1, B. J. Harvey1, W. Thomas1

Proc Physiol Soc 23 (2011)

Urinary aminopeptidase activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated rats

A. Quesada1, F. O'Valle2, M. Rodríguez-Martínez2, A. Segarra1, I. Prieto1, M. Ramírez1, F. Vargas3, R. Wangensteen1

Proc Physiol Soc 23 (2011)

Vascular Endothelial Growth Factor-A (VEGF-A) overexpression in adult mouse glomeruli increases glomerular ultrafiltration coefficient due partly to the reduced coverage of the capillaries by the subpodocyte space (SPS).

C. R. Neal1, P. Patel1, T. Ahad1, S. Oltean1, C. Alsop1, T. Lee1, K. Sison2, S. E. Quaggin2, S. J. Harper1, A. H. Salmon1,3, D. Bates1

Proc Physiol Soc 23 (2011)

The impact of NAD(P)H oxidase on the regulation of renal hemodynamics

H. F. Shabana1, A. F. Ahmeda1, E. J. Johns1

Proc Physiol Soc 23 (2011)

Bradykinin mediated activation of sensory nerves in the kidney: impact on contra-lateral kidney function

E. Barry1, E. J. Johns1

Proc Physiol Soc 23 (2011)

The role of Angiotensin (1-7) in the regulation of renal haemodynamics

J. O Neill1, N. Mc Conigley1, E. J. Johns1

Proc Physiol Soc 23 (2011)

Mirror-like SeSAME/EAST renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit

M. Paulais1, M. Bloch-Faure1, N. Picard1, T. Jacques1, S. Krishna Ramakrishnan1, M. Keck1, F. Sohet1, D. Eladari1, P. Houillier1, S. Lourdel1, J. Teulon1, S. J. Tucker2

Proc Physiol Soc 23 (2011)

Regulation of the epithelial sodium channel (ENaC) by norepinephrine in cultured mouse renal collecting duct cells

M. K. Mansley1, M. Bertog1, C. Korbmacher1

Proc Physiol Soc 23 (2011)

Impaired kidney function in rats six months after unilateral nephrectomy

V. Oršić1, M. Mihalj2, M. Moguš1, H. Mihalj3, M. Jakić4, M. Heffer Lauc5, L. Zibar1,4

Proc Physiol Soc 23 (2011)

AMP-activated protein kinase inhibits recombinant TASK-3 K+ channels

M. L. Dallas1, F. Ross2, J. L. Scragg1, C. N. Wyatt3, D. Hardie2, C. Peers1, A. Evans4

Proc Physiol Soc 20 (2010)

Modulation of Kv2.1 and Kv1.5 channels by AMP-activated protein kinase (AMPK)

M. L. Dallas1, J. Rafferty2, N. Ikematsu3, F. A. Ross3, D. Fedida4, D. Hardie3, C. Peers1, A. Evans2

Proc Physiol Soc 20 (2010)

Effects of chronic intermittent hypoxia on rat respiratory muscle structure and function

C. Shortt1, K. O'Halloran1, A. Bradford2

Proc Physiol Soc 20 (2010)

Respiratory muscle weakness following chronic intermittent hypoxia during early development in the rat.

R. A. O'Connell1, K. D. O'Halloran1

Proc Physiol Soc 20 (2010)

Classical model of ventilation applied to exercise in occupational lung disorders.

J. E. Cotes1,2, J. W. Reed1, D. W. Wilson2

Proc Physiol Soc 20 (2010)

Sternohyoid muscle function and MHC isoform expression in normoxic and chronically hypoxic rats during postnatal development

J. Carberry1, A. Bradford2, K. O'Halloran1

Proc Physiol Soc 20 (2010)

Ventilatory effects of chronic intermittent hypoxia in the rat.

D. Edge1, K. D. O'Halloran1

Proc Physiol Soc 20 (2010)

Functional analysis of novel CLCNKB mutations in patients with Bartter syndrome

M. Keck1, S. L'Hoste1, M. Genete1, M. El Hage1, T. Grand1, R. Vargas-Poussou2, A. Blanchard2, S. Lourdel1, J. Teulon1

Proc Physiol Soc 19 (2010)

The renal influence of endogenous urotensin II in the anaesthetised pre-hypertensive spontaneously hypertensive rat

E. Forty1, N. Ashton1

Proc Physiol Soc 19 (2010)

Multiphoton imaging of mitochondrial function in the isolated perfused rat kidney

A. Hall1, C. Crawford2, R. J. Unwin1, M. R. Duchen3, C. M. Peppiatt-Wildman2

Proc Physiol Soc 19 (2010)

Impact of gender on glomerular responses and inflammatory gene expression following juvenile onset obesity in sheep.

I. Bloor1, S. P. Sebert1, R. Mahajan1, M. E. Symonds1

Proc Physiol Soc 19 (2010)

Pathophysiological changes in extracellular pH regulate calcium-sensing receptor activity in HEK-293 and isolated parathyroid cells.

K. L. Campion1, W. D. McCormick1, R. Atkinson-Dell1, J. Warwicker1, D. T. Ward1

Proc Physiol Soc 19 (2010)

Antioxidant Treatment Rescues Salt-Sensitive Hypertension and Impaired Natriuresis in 11??-HSD2 Heterozygote Mice

E. Craigie1,2, J. J. Mullins2, M. A. Bailey2

Proc Physiol Soc 19 (2010)

Consequences of blocking Superoxide Dismutase (SOD) on renal haemodynamics in functioning and blocked Angiotensin (Ang) system in rats

F. B. O'Connor2,1, A. F. Ahmeda1,2

Proc Physiol Soc 19 (2010)

Maternal food restriction during pregnancy impairs offspring renal function in the rat

S. M. Almeshari1, N. Ashton2, G. Badr1, I. M. Alhazza1, S. H. Alwasel1

Proc Physiol Soc 19 (2010)