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The small molecule activator S3969 stimulates the human epithelial sodium channel (ENaC) by interacting with a specific binding pocket in the channelâ€™s Î²-subunit

A Ilyaskin, C Korbmacher, D Zahn, F Sure, J Einsiedel, P Duchstein and P Gmeiner

Proc Physiol Soc 51 (2023) C19

Modulation of Mitsugumin 23 by Zn2+ influences intracellular Ca2+ dyshomeostasis in cardiac cells.

AM Dorward, H Takeshima, M Nishi and SJ Pitt

Proc Physiol Soc 51 (2023) C15

Inhibition of Orai1 by a Novel Peptide (ELD607) Reduces Inflammation and Increases Survival in ÃŸENaC-Overexpressing Mice

B Grubb, E Worthington, R Tarran, S Ahmad and T Rodgers

Proc Physiol Soc 51 (2023) C17

The impact of acute potassium chloride infusion on renal haemodynamics and sodium excretion in anaesthetised rats.

A Arshad, J Ivy, K Stewart, M Bailey and N Dhaun

Proc Physiol Soc 51 (2023) C10

Acute activation of human ENaC by SGK1 depends on a highly conserved serine residue S594 in the channelâ€™s Î±-subunit and requires prior cleavage of the y-subunit at a putative furin cleavage site

A Diakov, A Ilyaskin, C Korbmacher and F Sure

Proc Physiol Soc 51 (2023) C14

N-linked glycosylation contributes to the absence of protease-sensitivity in epithelial sodium channels containing the Î´-subunit

D Kockler, EC Etang, F May, M Althaus and R Lawong

Proc Physiol Soc 51 (2023) C05

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