• 07 Jul 2019
  • Aberdeen Exhibition and Conference Centre, Aberdeen, UK

Renal physiology: Recent advances and emerging concepts

#

The Annual Conference is our flagship event and we want to continue to develop this so that it is more international in scope, provides a platform for dissemination of high quality research and appeals to the broadest physiology community. In addition, one of our key strategic objectives is to increase involvement of subdisciplines of physiology that are not well represented at our meetings. With this in mind, we are hosting a number of stimulating satellite symposia to complement Physiology 2019 on Sunday, 7 July 2019.

 

This satellite symposium, Renal physiology: Recent advances and emerging concepts, explores the latest advances in research behind the physiological processes related to the pathophysiology of such diseases as hypertension, diabetes, and kidney disease, and potential targets for novel therapies.

#
Sunday 7 July 2019

Registration and coffee

Welcome

Session 1

10:00 Modelling glomerular physiology using drosophila
Paul Hartley, Bournemouth University, UK
10:30 The mechanobiology of podocytes in health and disease
Paul Reynolds, University of St. Andrews, UK
11:00 Using multi-omics approaches to understand podocyte function
Markus Rinschen, University of Cologne, Germany 
11:30 PC08 Glomerular nephropathies in mice associated with VEGF splicing are ameliorated by SRPK1 inhibition
Andrew Benest, Univeristy of Nottingham , UK
11:45 Q&A

Lunch

Session 2

13:00 WNK/SPAK regulation of Na+ and K+ transport in the distal tubule
Juliette Hadchouel, Université Paris Sud, France
13:30 Role of ENaC in hypertension and Na+ retention in proteinuria
Boye Jensen, University of Southern Denmark, Denmark
14:00 Sex differences in renal transporters and electrolyte homeostasis: A female advantage?
Alicia McDonough, University of Southern California, USA
14:30 PC02 GR activation stimulates NCC and determines diurnal rhythm of its phosphorylation
Jessica Ivy, University of Edinburgh, UK
14:45 PC05 The physiological conundrum of inorganic phosphate stimulation of urinary ammonium excretion in the acidotic rabbit
Patrick Walsh, RCSI Bahrain, Bahrain

Break and refreshments

Session 3

15:30 The potassium switch in hypertension
Paul Welling, University of Maryland, USA
16:00 The role of the circadian clock in hypertension
Michelle Gumz, University of Florida, USA 
16:30 Vascular biology of hypertension
Rhian Touyz, University of Glasgow, UK
17:00 PC03 A role for male, but not female, macrophages in the clearance of endothelin-1
Greg Sutton, University of Edinburgh, UK
17:15 PC12 GPR81 activation causes endothelin-1 dependent renal vasoconstriction
Natalie Jones, University of Edinburgh, UK

Refreshments and poster session and posters

Whisy tasting

Coaches back to the city centre

#

You must be registered for Physiology 2019 to register for the ‘Cellular mechanisms of anti-cancer induced cardiotoxicity’ satellite symposium. To register for Physiology 2019 click here.

#

Travel

For information on travelling to Aberdeen, please see Visit Aberdeen.

Physiology 2019 will be hosted at the Aberdeen Exhibition and Conference Centre, Exhibition Ave, Bridge of Don, Aberdeen AB23 8BL. The AECC is the largest convention centre in northern Scotland, hosting 600 events and welcoming over 300,000 visitors each year.

AECC sits right next to the A90. It’s only a 15-minute taxi ride from Aberdeen railway and bus stations in the city centre.

By Bus

Organisers

Organiser:  Morag K Mansley, The University of Edinburgh, UK
Co-organiser:  Robert W Hunter, The University of Edinburgh, UK

#

Summary

Renal physiology is flourishing in the UK and around the world. In recent years physiologists have made fundamental advances: we now know the molecular basis of oedema formation in nephrotic syndrome, how renal sodium and potassium excretion can be controlled independently and how glomerular capillary permeability is regulated. We are learning much about the influence of the kidney on whole-organism physiology, in particular blood pressure homeostasis and circadian physiology.

In the current era, we are also witnessing a flourishing bi-directional relationship between advances in clinical medicine and mechanistic research into basic renal physiology. The bench-to-bedside journey is exemplified by sodium glucose co-transporter inhibitors (SGLTi). The physiological actions of these agents were meticulously defined in animal models. Now they have been shown to delay progression of diabetic nephropathy in large-scale clinical trials, so that we now have the first new effective treatment for this common condition in 15 years. On the other hand, clinical and epidemiological observations have thrown up fundamental physiological questions that have been answered in the laboratory (for example work exploring the consequences of pathological ApoL1 variants for podocyte biology).

This symposium aims to bring together scientists with a shared interest in renal physiology. We will focus on recent advances in three areas:

i)             glomerular physiology & pathophysiology

ii)            renal tubular transport

iii)           the kidney and hypertension

We aim to explore recent advances in basic renal physiology and consider how these are relevant for human kidney disease. We are delighted to welcome leading scientists from around the world to talk about their work alongside conference delegates. We hope that this will provide a vibrant forum for senior and early career researchers to discuss the hot topics in renal physiology today.

Site search

Filter

Content Type

Sign up to our newsletter

Sign up to our newsletter